Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats

10.1371/journal.pone.0041896

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Main Authors:	Kitada K., Nakano D., Liu Y., Fujisawa Y., Hitomi H., Shibayama Y., Shibata H., Nagai Y., Mori H., Masaki T., Kobori H., Nishiyama A.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	Public Library of Science 2020
Subjects:	eplerenone hydroethidine mineralocorticoid receptor paraquat protein p22 protein p22phox serum and glucocorticoid regulated kinase 1 tempol unclassified drug animal cell animal experiment animal tissue article blood pressure regulation controlled study Dahl salt sensitive rat genetic transcription glomerulus high sodium intake kidney injury male mesangium cell nonhuman oxidative stress podocyte protein function proteinuria receptor activation sodium restriction tissue level Adrenalectomy Aldosterone Animals Biological Markers Blood Pressure Cyclic N-Oxides Ethidium Feeding Behavior Genes, Reporter Immediate-Early Proteins Kidney Glomerulus Luciferases Male Mesangial Cells Mice Oxidative Stress Podocytes Protein-Serine-Threonine Kinases Proteinuria Rats Rats, Inbred Dahl Receptors, Mineralocorticoid Sodium Chloride, Dietary Sodium-Hydrogen Antiporter Spin Labels Systole Time Factors Rattus
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/165569
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1655692023-11-01T08:29:21Z Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats Kitada K. Nakano D. Liu Y. Fujisawa Y. Hitomi H. Shibayama Y. Shibata H. Nagai Y. Mori H. Masaki T. Kobori H. Nishiyama A. DUKE-NUS MEDICAL SCHOOL eplerenone hydroethidine mineralocorticoid receptor paraquat protein p22 protein p22phox serum and glucocorticoid regulated kinase 1 tempol unclassified drug animal cell animal experiment animal tissue article blood pressure regulation controlled study Dahl salt sensitive rat genetic transcription glomerulus high sodium intake kidney injury male mesangium cell nonhuman oxidative stress podocyte protein function proteinuria receptor activation sodium restriction tissue level Adrenalectomy Aldosterone Animals Biological Markers Blood Pressure Cyclic N-Oxides Ethidium Feeding Behavior Genes, Reporter Immediate-Early Proteins Kidney Glomerulus Luciferases Male Mesangial Cells Mice Oxidative Stress Podocytes Protein-Serine-Threonine Kinases Proteinuria Rats Rats, Inbred Dahl Receptors, Mineralocorticoid Sodium Chloride, Dietary Sodium-Hydrogen Antiporter Spin Labels Systole Time Factors Rattus 10.1371/journal.pone.0041896 PLoS ONE 7 7 e41896 2020-03-18T05:44:55Z 2020-03-18T05:44:55Z 2012 Article Kitada K., Nakano D., Liu Y., Fujisawa Y., Hitomi H., Shibayama Y., Shibata H., Nagai Y., Mori H., Masaki T., Kobori H., Nishiyama A. (2012). Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats. PLoS ONE 7 (7) : e41896. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0041896 19326203 https://scholarbank.nus.edu.sg/handle/10635/165569 Public Library of Science Unpaywall 20200320
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	eplerenone hydroethidine mineralocorticoid receptor paraquat protein p22 protein p22phox serum and glucocorticoid regulated kinase 1 tempol unclassified drug animal cell animal experiment animal tissue article blood pressure regulation controlled study Dahl salt sensitive rat genetic transcription glomerulus high sodium intake kidney injury male mesangium cell nonhuman oxidative stress podocyte protein function proteinuria receptor activation sodium restriction tissue level Adrenalectomy Aldosterone Animals Biological Markers Blood Pressure Cyclic N-Oxides Ethidium Feeding Behavior Genes, Reporter Immediate-Early Proteins Kidney Glomerulus Luciferases Male Mesangial Cells Mice Oxidative Stress Podocytes Protein-Serine-Threonine Kinases Proteinuria Rats Rats, Inbred Dahl Receptors, Mineralocorticoid Sodium Chloride, Dietary Sodium-Hydrogen Antiporter Spin Labels Systole Time Factors Rattus
spellingShingle	eplerenone hydroethidine mineralocorticoid receptor paraquat protein p22 protein p22phox serum and glucocorticoid regulated kinase 1 tempol unclassified drug animal cell animal experiment animal tissue article blood pressure regulation controlled study Dahl salt sensitive rat genetic transcription glomerulus high sodium intake kidney injury male mesangium cell nonhuman oxidative stress podocyte protein function proteinuria receptor activation sodium restriction tissue level Adrenalectomy Aldosterone Animals Biological Markers Blood Pressure Cyclic N-Oxides Ethidium Feeding Behavior Genes, Reporter Immediate-Early Proteins Kidney Glomerulus Luciferases Male Mesangial Cells Mice Oxidative Stress Podocytes Protein-Serine-Threonine Kinases Proteinuria Rats Rats, Inbred Dahl Receptors, Mineralocorticoid Sodium Chloride, Dietary Sodium-Hydrogen Antiporter Spin Labels Systole Time Factors Rattus Kitada K. Nakano D. Liu Y. Fujisawa Y. Hitomi H. Shibayama Y. Shibata H. Nagai Y. Mori H. Masaki T. Kobori H. Nishiyama A. Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats
description	10.1371/journal.pone.0041896
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Kitada K. Nakano D. Liu Y. Fujisawa Y. Hitomi H. Shibayama Y. Shibata H. Nagai Y. Mori H. Masaki T. Kobori H. Nishiyama A.
format	Article
author	Kitada K. Nakano D. Liu Y. Fujisawa Y. Hitomi H. Shibayama Y. Shibata H. Nagai Y. Mori H. Masaki T. Kobori H. Nishiyama A.
author_sort	Kitada K.
title	Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats
title_short	Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats
title_full	Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats
title_fullStr	Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats
title_full_unstemmed	Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats
title_sort	oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in dahl salt-sensitive rats
publisher	Public Library of Science
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/165569
_version_	1781791940671438848

Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats

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