MiR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis

10.1371/journal.pone.0033844

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Main Authors:	Silber J., Jacobsen A., Ozawa T., Harinath G., Pedraza A., Sander C., Holland E.C., Huse J.T.
Other Authors:	DEPT OF COMPUTER SCIENCE
Format:	Article
Published:	Public Library of Science 2020
Subjects:	microRNA microRNA 34a platelet derived growth factor platelet derived growth factor alpha receptor protein p53 unclassified drug animal experiment animal model article bioinformatics carcinogenesis cell growth cell proliferation controlled study down regulation gene regulatory network glioblastoma glioma cell growth inhibition human human tissue in vitro study in vivo study male mouse negative feedback nonhuman Animals Base Sequence Cell Cycle Checkpoints Cell Line Cell Proliferation Cell Transformation, Neoplastic Gene Expression Regulation, Neoplastic Glioma Humans Mice MicroRNAs Platelet-Derived Growth Factor Receptor, Platelet-Derived Growth Factor alpha Signal Transduction Tumor Suppressor Protein p53
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/165575
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1655752023-11-01T08:28:53Z MiR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis Silber J. Jacobsen A. Ozawa T. Harinath G. Pedraza A. Sander C. Holland E.C. Huse J.T. DEPT OF COMPUTER SCIENCE microRNA microRNA 34a platelet derived growth factor platelet derived growth factor alpha receptor protein p53 unclassified drug animal experiment animal model article bioinformatics carcinogenesis cell growth cell proliferation controlled study down regulation gene regulatory network glioblastoma glioma cell growth inhibition human human tissue in vitro study in vivo study male mouse negative feedback nonhuman Animals Base Sequence Cell Cycle Checkpoints Cell Line Cell Proliferation Cell Transformation, Neoplastic Gene Expression Regulation, Neoplastic Glioma Humans Mice MicroRNAs Platelet-Derived Growth Factor Receptor, Platelet-Derived Growth Factor alpha Signal Transduction Tumor Suppressor Protein p53 10.1371/journal.pone.0033844 PLoS ONE 7 3 e33844 2020-03-18T05:46:07Z 2020-03-18T05:46:07Z 2012 Article Silber J., Jacobsen A., Ozawa T., Harinath G., Pedraza A., Sander C., Holland E.C., Huse J.T. (2012). MiR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis. PLoS ONE 7 (3) : e33844. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0033844 19326203 https://scholarbank.nus.edu.sg/handle/10635/165575 Public Library of Science Unpaywall 20200320
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	microRNA microRNA 34a platelet derived growth factor platelet derived growth factor alpha receptor protein p53 unclassified drug animal experiment animal model article bioinformatics carcinogenesis cell growth cell proliferation controlled study down regulation gene regulatory network glioblastoma glioma cell growth inhibition human human tissue in vitro study in vivo study male mouse negative feedback nonhuman Animals Base Sequence Cell Cycle Checkpoints Cell Line Cell Proliferation Cell Transformation, Neoplastic Gene Expression Regulation, Neoplastic Glioma Humans Mice MicroRNAs Platelet-Derived Growth Factor Receptor, Platelet-Derived Growth Factor alpha Signal Transduction Tumor Suppressor Protein p53
spellingShingle	microRNA microRNA 34a platelet derived growth factor platelet derived growth factor alpha receptor protein p53 unclassified drug animal experiment animal model article bioinformatics carcinogenesis cell growth cell proliferation controlled study down regulation gene regulatory network glioblastoma glioma cell growth inhibition human human tissue in vitro study in vivo study male mouse negative feedback nonhuman Animals Base Sequence Cell Cycle Checkpoints Cell Line Cell Proliferation Cell Transformation, Neoplastic Gene Expression Regulation, Neoplastic Glioma Humans Mice MicroRNAs Platelet-Derived Growth Factor Receptor, Platelet-Derived Growth Factor alpha Signal Transduction Tumor Suppressor Protein p53 Silber J. Jacobsen A. Ozawa T. Harinath G. Pedraza A. Sander C. Holland E.C. Huse J.T. MiR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis
description	10.1371/journal.pone.0033844
author2	DEPT OF COMPUTER SCIENCE
author_facet	DEPT OF COMPUTER SCIENCE Silber J. Jacobsen A. Ozawa T. Harinath G. Pedraza A. Sander C. Holland E.C. Huse J.T.
format	Article
author	Silber J. Jacobsen A. Ozawa T. Harinath G. Pedraza A. Sander C. Holland E.C. Huse J.T.
author_sort	Silber J.
title	MiR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis
title_short	MiR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis
title_full	MiR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis
title_fullStr	MiR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis
title_full_unstemmed	MiR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis
title_sort	mir-34a repression in proneural malignant gliomas upregulates expression of its target pdgfra and promotes tumorigenesis
publisher	Public Library of Science
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/165575
_version_	1781791941463113728

MiR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis

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