VapC toxins from Mycobacterium tuberculosis are ribonucleases that differentially inhibit growth and are neutralized by cognate vapB antitoxins

VapC toxins from Mycobacterium tuberculosis are ribonucleases that differentially inhibit growth and are neutralized by cognate vapB antitoxins

10.1371/journal.pone.0021738

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Bibliographic Details
Main Authors:	Ahidjo B.A., Kuhnert D., McKenzie J.L., Machowski E.E., Gordhan B.G., Arcus V., Abrahams G.L., Mizrahi V.
Other Authors:	MICROBIOLOGY AND IMMUNOLOGY
Format:	Article
Published:	Public Library of Science 2020
Subjects:	antitoxin bacterial toxin ribonuclease tetracycline unclassified drug vapB toxin vapC toxin bacterial protein article bacterial gene bacterial growth controlled study enzyme activity gene deletion gene expression regulation gene function gene locus gene overexpression genetic selection growth inhibition Mycobacterium smegmatis Mycobacterium tuberculosis nonhuman operon phenotype promoter region protein expression protein function protein protein interaction toxin analysis genetics growth, development and aging metabolism physiology Antitoxins Bacterial Proteins Gene Expression Regulation, Bacterial Ribonucleases
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/165590
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Institution:	National University of Singapore

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