A RNA Interference Screen Identifies the Protein Phosphatase 2A Subunit PR55γ as a Stress-Sensitive Inhibitor of c-SRC

• Main Authors: Eichhorn P.J.A., Creyghton M.P., Wilhelmsen K., Van Dam H., Bernards R.
• Other Authors: DEPT OF PHARMACOLOGY
• Format: Article
• Published: Public Library of Science 2020
• Subjects: mitogen activated protein kinase; phosphoprotein phosphatase inhibitor; pr 55 delta; pr55 gamma; serine; unclassified drug; CSK protein, human; oncoprotein; phosphoprotein phosphatase 2; PPP2R2C protein, human; primer DNA; protein tyrosine kinase; stress activated protein kinase; article; drug inhibition; enzyme activity; gene control; gene repression; human; oncogene; phosphorylation; protein analysis; protein protein interaction; RNA interference; ultraviolet irradiation; amino acid substitution; apoptosis; cell line; chemistry; drug antagonism; enzyme activation; genetic transfection; genetics; metabolism; nucleotide sequence; physiology; radiation exposure; signal transduction; site directed mutagenesis; ultraviolet radiation; Amino Acid Substitution; Apoptosis; Base Sequence; Cell Line; DNA Primers; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Phosphorylation; Protein Phosphatase 2; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; RNA Interference; Serine; Signal Transduction; Transfection; Ultraviolet Rays
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165612
• Institution: National University of Singapore

10.1371/journal.pgen.0030218