A RNA Interference Screen Identifies the Protein Phosphatase 2A Subunit PR55γ as a Stress-Sensitive Inhibitor of c-SRC

10.1371/journal.pgen.0030218

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Main Authors: Eichhorn P.J.A., Creyghton M.P., Wilhelmsen K., Van Dam H., Bernards R.
Other Authors: PHARMACOLOGY
Format: Article
Published: Public Library of Science 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/165612
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spelling sg-nus-scholar.10635-1656122024-11-10T23:26:30Z A RNA Interference Screen Identifies the Protein Phosphatase 2A Subunit PR55γ as a Stress-Sensitive Inhibitor of c-SRC Eichhorn P.J.A. Creyghton M.P. Wilhelmsen K. Van Dam H. Bernards R. PHARMACOLOGY mitogen activated protein kinase phosphoprotein phosphatase inhibitor pr 55 delta pr55 gamma serine unclassified drug CSK protein, human oncoprotein phosphoprotein phosphatase 2 PPP2R2C protein, human primer DNA protein tyrosine kinase stress activated protein kinase article drug inhibition enzyme activity gene control gene repression human oncogene phosphorylation protein analysis protein protein interaction RNA interference ultraviolet irradiation amino acid substitution apoptosis cell line chemistry drug antagonism enzyme activation genetic transfection genetics metabolism nucleotide sequence physiology radiation exposure signal transduction site directed mutagenesis ultraviolet radiation Amino Acid Substitution Apoptosis Base Sequence Cell Line DNA Primers Enzyme Activation Humans JNK Mitogen-Activated Protein Kinases Mutagenesis, Site-Directed Phosphorylation Protein Phosphatase 2 Protein-Tyrosine Kinases Proto-Oncogene Proteins RNA Interference Serine Signal Transduction Transfection Ultraviolet Rays 10.1371/journal.pgen.0030218 PLoS Genetics 3 12 2381-2394 2020-03-18T05:53:35Z 2020-03-18T05:53:35Z 2007 Article Eichhorn P.J.A., Creyghton M.P., Wilhelmsen K., Van Dam H., Bernards R. (2007). A RNA Interference Screen Identifies the Protein Phosphatase 2A Subunit PR55γ as a Stress-Sensitive Inhibitor of c-SRC. PLoS Genetics 3 (12) : 2381-2394. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pgen.0030218 15537390 https://scholarbank.nus.edu.sg/handle/10635/165612 Public Library of Science Unpaywall 20200320
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic mitogen activated protein kinase
phosphoprotein phosphatase inhibitor
pr 55 delta
pr55 gamma
serine
unclassified drug
CSK protein, human
oncoprotein
phosphoprotein phosphatase 2
PPP2R2C protein, human
primer DNA
protein tyrosine kinase
stress activated protein kinase
article
drug inhibition
enzyme activity
gene control
gene repression
human
oncogene
phosphorylation
protein analysis
protein protein interaction
RNA interference
ultraviolet irradiation
amino acid substitution
apoptosis
cell line
chemistry
drug antagonism
enzyme activation
genetic transfection
genetics
metabolism
nucleotide sequence
physiology
radiation exposure
signal transduction
site directed mutagenesis
ultraviolet radiation
Amino Acid Substitution
Apoptosis
Base Sequence
Cell Line
DNA Primers
Enzyme Activation
Humans
JNK Mitogen-Activated Protein Kinases
Mutagenesis, Site-Directed
Phosphorylation
Protein Phosphatase 2
Protein-Tyrosine Kinases
Proto-Oncogene Proteins
RNA Interference
Serine
Signal Transduction
Transfection
Ultraviolet Rays
spellingShingle mitogen activated protein kinase
phosphoprotein phosphatase inhibitor
pr 55 delta
pr55 gamma
serine
unclassified drug
CSK protein, human
oncoprotein
phosphoprotein phosphatase 2
PPP2R2C protein, human
primer DNA
protein tyrosine kinase
stress activated protein kinase
article
drug inhibition
enzyme activity
gene control
gene repression
human
oncogene
phosphorylation
protein analysis
protein protein interaction
RNA interference
ultraviolet irradiation
amino acid substitution
apoptosis
cell line
chemistry
drug antagonism
enzyme activation
genetic transfection
genetics
metabolism
nucleotide sequence
physiology
radiation exposure
signal transduction
site directed mutagenesis
ultraviolet radiation
Amino Acid Substitution
Apoptosis
Base Sequence
Cell Line
DNA Primers
Enzyme Activation
Humans
JNK Mitogen-Activated Protein Kinases
Mutagenesis, Site-Directed
Phosphorylation
Protein Phosphatase 2
Protein-Tyrosine Kinases
Proto-Oncogene Proteins
RNA Interference
Serine
Signal Transduction
Transfection
Ultraviolet Rays
Eichhorn P.J.A.
Creyghton M.P.
Wilhelmsen K.
Van Dam H.
Bernards R.
A RNA Interference Screen Identifies the Protein Phosphatase 2A Subunit PR55γ as a Stress-Sensitive Inhibitor of c-SRC
description 10.1371/journal.pgen.0030218
author2 PHARMACOLOGY
author_facet PHARMACOLOGY
Eichhorn P.J.A.
Creyghton M.P.
Wilhelmsen K.
Van Dam H.
Bernards R.
format Article
author Eichhorn P.J.A.
Creyghton M.P.
Wilhelmsen K.
Van Dam H.
Bernards R.
author_sort Eichhorn P.J.A.
title A RNA Interference Screen Identifies the Protein Phosphatase 2A Subunit PR55γ as a Stress-Sensitive Inhibitor of c-SRC
title_short A RNA Interference Screen Identifies the Protein Phosphatase 2A Subunit PR55γ as a Stress-Sensitive Inhibitor of c-SRC
title_full A RNA Interference Screen Identifies the Protein Phosphatase 2A Subunit PR55γ as a Stress-Sensitive Inhibitor of c-SRC
title_fullStr A RNA Interference Screen Identifies the Protein Phosphatase 2A Subunit PR55γ as a Stress-Sensitive Inhibitor of c-SRC
title_full_unstemmed A RNA Interference Screen Identifies the Protein Phosphatase 2A Subunit PR55γ as a Stress-Sensitive Inhibitor of c-SRC
title_sort rna interference screen identifies the protein phosphatase 2a subunit pr55γ as a stress-sensitive inhibitor of c-src
publisher Public Library of Science
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/165612
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