Prediction of long-term benefits of inhaled steroids by phenotypic markers in moderateto-severe COPD: A randomized controlled trial

• Main Authors: Snoeck-Stroband J.B., Lapperre T.S., Sterk P.J., Hiemstra P.S., Thiadens H.A., Boezen H.M., Ten Hacken N.H.T., Kerstjens H.A.M., Postma D.S., Timens W., Sont J.K.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Public Library of Science 2020
• Subjects: fluticasone propionate; placebo; bronchodilating agent; corticosteroid; fluticasone; adult; aged; Article; cell count; chronic obstructive lung disease; clinical effectiveness; controlled study; disease severity; double blind procedure; drug efficacy; dyspnea; female; forced expiratory volume; health status; human; inflammatory cell; lung diffusion capacity; major clinical study; male; multicenter study; phenotype; prediction; randomized controlled trial; smoking; treatment duration; treatment outcome; clinical trial; drug administration; inhalational drug administration; lung; middle aged; pathology; pathophysiology; physiology; placebo effect; Pulmonary Disease, Chronic Obstructive; severity of illness index; spirometry; sputum; Administration, Inhalation; Adrenal Cortex Hormones; Aged; Bronchodilator Agents; Drug Administration Schedule; Female; Fluticasone; Forced Expiratory Volume; Humans; Lung; Male; Middle Aged; Phenotype; Placebo Effect; Severity of Illness Index; Spirometry; Sputum; Treatment Outcome
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165757
• Institution: National University of Singapore

10.1371/journal.pone.0143793