Validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer

10.1371/journal.pone.0184372

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Main Authors:	Cheng, S.H.-C, Huang, T.-T, Cheng, Y.-H., Tan, T.B.K., Horng, C.-F., Wang, Y.A., Brian, N.S., Shih, L.-S., Yu, B.-L.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	Public Library of Science 2020
Subjects:	chemokine receptor CCR1 matrix metalloproteinase 15 protein kinase Pim 1 transcription factor 7 like 1 vanilloid receptor 6 tumor marker adult Article BLM gene breast cancer breast surgery BUB1B gene C16ORF7 gene cancer prognosis cancer staging CCNB1 gene CCR1 gene classifier DDX39 gene distant metastasis DTX2 gene ENSA gene external validity gene gene classifier genetic algorithm high risk patient human human tissue internal validity low risk patient major clinical study MMP15 gene NFATC2IP gene OBSL1 gene PIM1 gene probability PTI1 gene RCHY1 gene risk assessment scoring system STIL gene TCF3 gene TPX2 gene TRPV6 gene aged Breast Neoplasms cancer grading female gene expression profiling genetics metastasis middle aged mortality multimodality cancer therapy pathology prognosis proportional hazards model reproducibility young adult Adult Aged Biomarkers, Tumor Combined Modality Therapy Female Gene Expression Profiling Humans Middle Aged Neoplasm Grading Neoplasm Metastasis Neoplasm Staging Prognosis Proportional Hazards Models Reproducibility of Results Young Adult
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/165779
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1657792023-10-31T20:51:07Z Validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer Cheng, S.H.-C Huang, T.-T Cheng, Y.-H. Tan, T.B.K. Horng, C.-F. Wang, Y.A. Brian, N.S. Shih, L.-S. Yu, B.-L. DUKE-NUS MEDICAL SCHOOL chemokine receptor CCR1 matrix metalloproteinase 15 protein kinase Pim 1 transcription factor 7 like 1 vanilloid receptor 6 tumor marker adult Article BLM gene breast cancer breast surgery BUB1B gene C16ORF7 gene cancer prognosis cancer staging CCNB1 gene CCR1 gene classifier DDX39 gene distant metastasis DTX2 gene ENSA gene external validity gene gene classifier genetic algorithm high risk patient human human tissue internal validity low risk patient major clinical study MMP15 gene NFATC2IP gene OBSL1 gene PIM1 gene probability PTI1 gene RCHY1 gene risk assessment scoring system STIL gene TCF3 gene TPX2 gene TRPV6 gene aged Breast Neoplasms cancer grading female gene expression profiling genetics metastasis middle aged mortality multimodality cancer therapy pathology prognosis proportional hazards model reproducibility young adult Adult Aged Biomarkers, Tumor Breast Neoplasms Combined Modality Therapy Female Gene Expression Profiling Humans Middle Aged Neoplasm Grading Neoplasm Metastasis Neoplasm Staging Prognosis Proportional Hazards Models Reproducibility of Results Young Adult 10.1371/journal.pone.0184372 PLoS ONE 12 9 e0184372 2020-03-19T09:00:10Z 2020-03-19T09:00:10Z 2017 Article Cheng, S.H.-C, Huang, T.-T, Cheng, Y.-H., Tan, T.B.K., Horng, C.-F., Wang, Y.A., Brian, N.S., Shih, L.-S., Yu, B.-L. (2017). Validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer. PLoS ONE 12 (9) : e0184372. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0184372 1932-6203 https://scholarbank.nus.edu.sg/handle/10635/165779 Public Library of Science Unpaywall 20200320
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	chemokine receptor CCR1 matrix metalloproteinase 15 protein kinase Pim 1 transcription factor 7 like 1 vanilloid receptor 6 tumor marker adult Article BLM gene breast cancer breast surgery BUB1B gene C16ORF7 gene cancer prognosis cancer staging CCNB1 gene CCR1 gene classifier DDX39 gene distant metastasis DTX2 gene ENSA gene external validity gene gene classifier genetic algorithm high risk patient human human tissue internal validity low risk patient major clinical study MMP15 gene NFATC2IP gene OBSL1 gene PIM1 gene probability PTI1 gene RCHY1 gene risk assessment scoring system STIL gene TCF3 gene TPX2 gene TRPV6 gene aged Breast Neoplasms cancer grading female gene expression profiling genetics metastasis middle aged mortality multimodality cancer therapy pathology prognosis proportional hazards model reproducibility young adult Adult Aged Biomarkers, Tumor Breast Neoplasms Combined Modality Therapy Female Gene Expression Profiling Humans Middle Aged Neoplasm Grading Neoplasm Metastasis Neoplasm Staging Prognosis Proportional Hazards Models Reproducibility of Results Young Adult
spellingShingle	chemokine receptor CCR1 matrix metalloproteinase 15 protein kinase Pim 1 transcription factor 7 like 1 vanilloid receptor 6 tumor marker adult Article BLM gene breast cancer breast surgery BUB1B gene C16ORF7 gene cancer prognosis cancer staging CCNB1 gene CCR1 gene classifier DDX39 gene distant metastasis DTX2 gene ENSA gene external validity gene gene classifier genetic algorithm high risk patient human human tissue internal validity low risk patient major clinical study MMP15 gene NFATC2IP gene OBSL1 gene PIM1 gene probability PTI1 gene RCHY1 gene risk assessment scoring system STIL gene TCF3 gene TPX2 gene TRPV6 gene aged Breast Neoplasms cancer grading female gene expression profiling genetics metastasis middle aged mortality multimodality cancer therapy pathology prognosis proportional hazards model reproducibility young adult Adult Aged Biomarkers, Tumor Breast Neoplasms Combined Modality Therapy Female Gene Expression Profiling Humans Middle Aged Neoplasm Grading Neoplasm Metastasis Neoplasm Staging Prognosis Proportional Hazards Models Reproducibility of Results Young Adult Cheng, S.H.-C Huang, T.-T Cheng, Y.-H. Tan, T.B.K. Horng, C.-F. Wang, Y.A. Brian, N.S. Shih, L.-S. Yu, B.-L. Validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer
description	10.1371/journal.pone.0184372
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Cheng, S.H.-C Huang, T.-T Cheng, Y.-H. Tan, T.B.K. Horng, C.-F. Wang, Y.A. Brian, N.S. Shih, L.-S. Yu, B.-L.
format	Article
author	Cheng, S.H.-C Huang, T.-T Cheng, Y.-H. Tan, T.B.K. Horng, C.-F. Wang, Y.A. Brian, N.S. Shih, L.-S. Yu, B.-L.
author_sort	Cheng, S.H.-C
title	Validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer
title_short	Validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer
title_full	Validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer
title_fullStr	Validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer
title_full_unstemmed	Validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer
title_sort	validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer
publisher	Public Library of Science
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/165779
_version_	1781791977561391104

Validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer

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