Regulation of the NRF2 transcription factor by andrographolide and organic extracts from plant endophytes

10.1371/journal.pone.0204853

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Main Authors:	Wen Wong D.P., Ng M.Y., Leung J.Y., Boh B.K., Lim E.C., Tan S.H., Lim S., Seah W.H., Hu C.Z., Ho B.C., Ng D.H.P., Hagen T.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	Public Library of Science 2020
Subjects:	andrographolide cullin cullin 3 kelch like ECH associated protein 1 protein RBX1 RING finger protein sulforaphane transcription factor Nrf2 unclassified drug carrier protein CUL3 protein, human diterpene KEAP1 protein, human NFE2L2 protein, human plant extract protein binding RBX1 protein, human Article binding affinity Calymperes erosum Campylopus serratus densitometry Dicranopteris linearis endophyte enzyme activity fern human human cell moss nonhuman Ophioglossum reticulatum Philonotis thwaitesii Phlegmariurus phlegmaria protein degradation protein expression protein function protein interaction protein localization protein processing protein stability Psilotum nudum Pyrrosia piloselloides Taenitis blechnoides ubiquitination Vesicularia dubyana binding site chemistry drug effect gene expression regulation HEK293 cell line metabolism secondary metabolism Binding Sites Bryophyta Carrier Proteins Cullin Proteins Diterpenes Endophytes Ferns Gene Expression Regulation HEK293 Cells Humans Kelch-Like ECH-Associated Protein 1 NF-E2-Related Factor 2 Plant Extracts Protein Binding Secondary Metabolism Ubiquitination
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/165895
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1658952024-04-22T03:16:58Z Regulation of the NRF2 transcription factor by andrographolide and organic extracts from plant endophytes Wen Wong D.P. Ng M.Y. Leung J.Y. Boh B.K. Lim E.C. Tan S.H. Lim S. Seah W.H. Hu C.Z. Ho B.C. Ng D.H.P. Hagen T. DUKE-NUS MEDICAL SCHOOL BIOCHEMISTRY OFFICE OF SAFETY, HEALTH AND ENVIRONMENT andrographolide cullin cullin 3 kelch like ECH associated protein 1 protein RBX1 RING finger protein sulforaphane transcription factor Nrf2 unclassified drug andrographolide carrier protein CUL3 protein, human cullin diterpene KEAP1 protein, human kelch like ECH associated protein 1 NFE2L2 protein, human plant extract protein binding RBX1 protein, human transcription factor Nrf2 Article binding affinity Calymperes erosum Campylopus serratus densitometry Dicranopteris linearis endophyte enzyme activity fern human human cell moss nonhuman Ophioglossum reticulatum Philonotis thwaitesii Phlegmariurus phlegmaria protein binding protein degradation protein expression protein function protein interaction protein localization protein processing protein stability Psilotum nudum Pyrrosia piloselloides Taenitis blechnoides ubiquitination Vesicularia dubyana binding site chemistry drug effect endophyte gene expression regulation HEK293 cell line metabolism secondary metabolism Binding Sites Bryophyta Carrier Proteins Cullin Proteins Diterpenes Endophytes Ferns Gene Expression Regulation HEK293 Cells Humans Kelch-Like ECH-Associated Protein 1 NF-E2-Related Factor 2 Plant Extracts Protein Binding Secondary Metabolism Ubiquitination 10.1371/journal.pone.0204853 PLoS ONE 13 10 e0204853 2020-03-23T06:19:07Z 2020-03-23T06:19:07Z 2018 Article Wen Wong D.P., Ng M.Y., Leung J.Y., Boh B.K., Lim E.C., Tan S.H., Lim S., Seah W.H., Hu C.Z., Ho B.C., Ng D.H.P., Hagen T. (2018). Regulation of the NRF2 transcription factor by andrographolide and organic extracts from plant endophytes. PLoS ONE 13 (10) : e0204853. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0204853 19326203 https://scholarbank.nus.edu.sg/handle/10635/165895 Public Library of Science Unpaywall 20200320
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	andrographolide cullin cullin 3 kelch like ECH associated protein 1 protein RBX1 RING finger protein sulforaphane transcription factor Nrf2 unclassified drug andrographolide carrier protein CUL3 protein, human cullin diterpene KEAP1 protein, human kelch like ECH associated protein 1 NFE2L2 protein, human plant extract protein binding RBX1 protein, human transcription factor Nrf2 Article binding affinity Calymperes erosum Campylopus serratus densitometry Dicranopteris linearis endophyte enzyme activity fern human human cell moss nonhuman Ophioglossum reticulatum Philonotis thwaitesii Phlegmariurus phlegmaria protein binding protein degradation protein expression protein function protein interaction protein localization protein processing protein stability Psilotum nudum Pyrrosia piloselloides Taenitis blechnoides ubiquitination Vesicularia dubyana binding site chemistry drug effect endophyte gene expression regulation HEK293 cell line metabolism secondary metabolism Binding Sites Bryophyta Carrier Proteins Cullin Proteins Diterpenes Endophytes Ferns Gene Expression Regulation HEK293 Cells Humans Kelch-Like ECH-Associated Protein 1 NF-E2-Related Factor 2 Plant Extracts Protein Binding Secondary Metabolism Ubiquitination
spellingShingle	andrographolide cullin cullin 3 kelch like ECH associated protein 1 protein RBX1 RING finger protein sulforaphane transcription factor Nrf2 unclassified drug andrographolide carrier protein CUL3 protein, human cullin diterpene KEAP1 protein, human kelch like ECH associated protein 1 NFE2L2 protein, human plant extract protein binding RBX1 protein, human transcription factor Nrf2 Article binding affinity Calymperes erosum Campylopus serratus densitometry Dicranopteris linearis endophyte enzyme activity fern human human cell moss nonhuman Ophioglossum reticulatum Philonotis thwaitesii Phlegmariurus phlegmaria protein binding protein degradation protein expression protein function protein interaction protein localization protein processing protein stability Psilotum nudum Pyrrosia piloselloides Taenitis blechnoides ubiquitination Vesicularia dubyana binding site chemistry drug effect endophyte gene expression regulation HEK293 cell line metabolism secondary metabolism Binding Sites Bryophyta Carrier Proteins Cullin Proteins Diterpenes Endophytes Ferns Gene Expression Regulation HEK293 Cells Humans Kelch-Like ECH-Associated Protein 1 NF-E2-Related Factor 2 Plant Extracts Protein Binding Secondary Metabolism Ubiquitination Wen Wong D.P. Ng M.Y. Leung J.Y. Boh B.K. Lim E.C. Tan S.H. Lim S. Seah W.H. Hu C.Z. Ho B.C. Ng D.H.P. Hagen T. Regulation of the NRF2 transcription factor by andrographolide and organic extracts from plant endophytes
description	10.1371/journal.pone.0204853
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Wen Wong D.P. Ng M.Y. Leung J.Y. Boh B.K. Lim E.C. Tan S.H. Lim S. Seah W.H. Hu C.Z. Ho B.C. Ng D.H.P. Hagen T.
format	Article
author	Wen Wong D.P. Ng M.Y. Leung J.Y. Boh B.K. Lim E.C. Tan S.H. Lim S. Seah W.H. Hu C.Z. Ho B.C. Ng D.H.P. Hagen T.
author_sort	Wen Wong D.P.
title	Regulation of the NRF2 transcription factor by andrographolide and organic extracts from plant endophytes
title_short	Regulation of the NRF2 transcription factor by andrographolide and organic extracts from plant endophytes
title_full	Regulation of the NRF2 transcription factor by andrographolide and organic extracts from plant endophytes
title_fullStr	Regulation of the NRF2 transcription factor by andrographolide and organic extracts from plant endophytes
title_full_unstemmed	Regulation of the NRF2 transcription factor by andrographolide and organic extracts from plant endophytes
title_sort	regulation of the nrf2 transcription factor by andrographolide and organic extracts from plant endophytes
publisher	Public Library of Science
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/165895
_version_	1800913931430002688

Regulation of the NRF2 transcription factor by andrographolide and organic extracts from plant endophytes

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