CMV latent infection improves CD8+ T response to SEB due to expansion of polyfunctional CD57+ cells in young individuals

• Main Authors: Pera A., Campos C., Corona A., Sanchez-Correa B., Tarazona R., Larbi A., Solana R.
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: Public Library of Science 2020
• Subjects: CD57 antigen; gamma interferon; lysosome associated membrane protein 1; Staphylococcus enterotoxin B; tumor necrosis factor alpha; CD3 antigen; enterotoxin; enterotoxin B, staphylococcal; adult; antigen expression; article; CD57+ T lymphocyte; CD8+ T lymphocyte; cell expansion; clinical article; controlled study; cytokine production; cytomegalovirus infection; degranulation; female; human; human cell; immune response; lymphocyte function; lymphocyte proliferation; male; middle aged; T lymphocyte; adolescent; age; chemistry; cytology; flow cytometry; gene expression regulation; immunology; metabolism; mononuclear cell; young adult; Adolescent; Adult; Age Factors; Antigens, CD3; Antigens, CD57; CD8-Positive T-Lymphocytes; Cytomegalovirus Infections; Enterotoxins; Female; Flow Cytometry; Gene Expression Regulation; Humans; Interferon-gamma; Leukocytes, Mononuclear; Lysosomal-Associated Membrane Protein 1; Male; Middle Aged; Tumor Necrosis Factor-alpha; Young Adult
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165959
• Institution: National University of Singapore

10.1371/journal.pone.0088538