Astrocyte-derived proinflammatory cytokines induce hypomyelination in the periventricular white matter in the hypoxic neonatal brain
10.1371/journal.pone.0087420
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sg-nus-scholar.10635-1659612024-04-08T14:33:33Z Astrocyte-derived proinflammatory cytokines induce hypomyelination in the periventricular white matter in the hypoxic neonatal brain Deng Y. Xie D. Fang M. Zhu G. Chen C. Zeng H. Lu J. Charanjit K. ANATOMY interleukin 1 receptor type I interleukin 1beta tumor necrosis factor alpha tumor necrosis factor receptor 1 animal cell animal experiment animal model animal tissue antigen presenting cell apoptosis article astrocyte brain hypoxia cell culture controlled study demyelination electron microscopy female hypomyelination immunofluorescence immunopathogenesis myelination nerve fiber nonhuman oligodendroglia periventricular white matter disorder protein expression real time polymerase chain reaction upregulation Western blotting white matter lesion Wistar rat Animals Animals, Newborn Apoptosis Astrocytes Cell Hypoxia Cells, Cultured Cerebral Cortex Demyelinating Diseases Hypoxia, Brain Inflammation Mediators Interleukin-1beta Myelin Sheath Oligodendroglia Rats Rats, Wistar Tumor Necrosis Factor-alpha Up-Regulation 10.1371/journal.pone.0087420 PLoS ONE 9 1 e87420 2020-03-26T06:44:22Z 2020-03-26T06:44:22Z 2014 Article Deng Y., Xie D., Fang M., Zhu G., Chen C., Zeng H., Lu J., Charanjit K. (2014). Astrocyte-derived proinflammatory cytokines induce hypomyelination in the periventricular white matter in the hypoxic neonatal brain. PLoS ONE 9 (1) : e87420. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0087420 19326203 https://scholarbank.nus.edu.sg/handle/10635/165961 Public Library of Science Unpaywall 20200320 |
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interleukin 1 receptor type I interleukin 1beta tumor necrosis factor alpha tumor necrosis factor receptor 1 animal cell animal experiment animal model animal tissue antigen presenting cell apoptosis article astrocyte brain hypoxia cell culture controlled study demyelination electron microscopy female hypomyelination immunofluorescence immunopathogenesis myelination nerve fiber nonhuman oligodendroglia periventricular white matter disorder protein expression real time polymerase chain reaction upregulation Western blotting white matter lesion Wistar rat Animals Animals, Newborn Apoptosis Astrocytes Cell Hypoxia Cells, Cultured Cerebral Cortex Demyelinating Diseases Hypoxia, Brain Inflammation Mediators Interleukin-1beta Myelin Sheath Oligodendroglia Rats Rats, Wistar Tumor Necrosis Factor-alpha Up-Regulation |
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interleukin 1 receptor type I interleukin 1beta tumor necrosis factor alpha tumor necrosis factor receptor 1 animal cell animal experiment animal model animal tissue antigen presenting cell apoptosis article astrocyte brain hypoxia cell culture controlled study demyelination electron microscopy female hypomyelination immunofluorescence immunopathogenesis myelination nerve fiber nonhuman oligodendroglia periventricular white matter disorder protein expression real time polymerase chain reaction upregulation Western blotting white matter lesion Wistar rat Animals Animals, Newborn Apoptosis Astrocytes Cell Hypoxia Cells, Cultured Cerebral Cortex Demyelinating Diseases Hypoxia, Brain Inflammation Mediators Interleukin-1beta Myelin Sheath Oligodendroglia Rats Rats, Wistar Tumor Necrosis Factor-alpha Up-Regulation Deng Y. Xie D. Fang M. Zhu G. Chen C. Zeng H. Lu J. Charanjit K. Astrocyte-derived proinflammatory cytokines induce hypomyelination in the periventricular white matter in the hypoxic neonatal brain |
| description |
10.1371/journal.pone.0087420 |
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ANATOMY |
| author_facet |
ANATOMY Deng Y. Xie D. Fang M. Zhu G. Chen C. Zeng H. Lu J. Charanjit K. |
| format |
Article |
| author |
Deng Y. Xie D. Fang M. Zhu G. Chen C. Zeng H. Lu J. Charanjit K. |
| author_sort |
Deng Y. |
| title |
Astrocyte-derived proinflammatory cytokines induce hypomyelination in the periventricular white matter in the hypoxic neonatal brain |
| title_short |
Astrocyte-derived proinflammatory cytokines induce hypomyelination in the periventricular white matter in the hypoxic neonatal brain |
| title_full |
Astrocyte-derived proinflammatory cytokines induce hypomyelination in the periventricular white matter in the hypoxic neonatal brain |
| title_fullStr |
Astrocyte-derived proinflammatory cytokines induce hypomyelination in the periventricular white matter in the hypoxic neonatal brain |
| title_full_unstemmed |
Astrocyte-derived proinflammatory cytokines induce hypomyelination in the periventricular white matter in the hypoxic neonatal brain |
| title_sort |
astrocyte-derived proinflammatory cytokines induce hypomyelination in the periventricular white matter in the hypoxic neonatal brain |
| publisher |
Public Library of Science |
| publishDate |
2020 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/165961 |
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