Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese

10.1371/journal.pone.0084770

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Main Authors:	Ma R.C.W., Lee H.M., Lam V.K.L., Tam C.H.T., Ho J.S.K., Zhao H.-L., Guan J., Kong A.P.S., Lau E., Zhang G., Luk A., Wang Y., Tsui S.K.W., Chan T.F., Hu C., Jia W.P., Park K.S., Lee H.K., Furuta H., Nanjo K., Shyong Tai E., Ng D.P.-K., Tang N.L.S., Woo J., Leung P.C., Xue H., Wong J., Leung P.S., Lau T.C.K., Tong P.C.Y., Xu G., Ng M.C.Y., So W.Y., Chan J.C.N.
Other Authors:	SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
Format:	Article
Published:	Public Library of Science 2020
Subjects:	insulin DACH1 protein, human eye protein transcription factor adult article Asian autopsy bioinformatics cardiovascular disease case control study Chinese cohort analysis controlled study coronary artery atherosclerosis Dachshund homolog 1 gene diabetes mellitus familial young onset diabetes mellitus female gene gene expression genetic analysis genetic association genetic variability human human cell human tissue impaired glucose tolerance insulin release insulin resistance intron ischemic heart disease major clinical study male molecular pathology non insulin dependent diabetes mellitus peripheral blood mononuclear cell regulatory sequence single nucleotide polymorphism systolic blood pressure aged Asian continental ancestry group Cardiovascular Diseases Diabetes Mellitus, Type 2 genetic predisposition genetics genotype middle aged Prediabetic State Aged Asian Continental Ancestry Group Case-Control Studies Eye Proteins Female Genetic Predisposition to Disease Genome-Wide Association Study Genotype Humans Male Middle Aged Polymorphism, Single Nucleotide Transcription Factors
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/165964
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1659642023-10-31T08:45:15Z Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese Ma R.C.W. Lee H.M. Lam V.K.L. Tam C.H.T. Ho J.S.K. Zhao H.-L. Guan J. Kong A.P.S. Lau E. Zhang G. Luk A. Wang Y. Tsui S.K.W. Chan T.F. Hu C. Jia W.P. Park K.S. Lee H.K. Furuta H. Nanjo K. Shyong Tai E. Ng D.P.-K. Tang N.L.S. Woo J. Leung P.C. Xue H. Wong J. Leung P.S. Lau T.C.K. Tong P.C.Y. Xu G. Ng M.C.Y. So W.Y. Chan J.C.N. SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH insulin DACH1 protein, human eye protein transcription factor adult article Asian autopsy bioinformatics cardiovascular disease case control study Chinese cohort analysis controlled study coronary artery atherosclerosis Dachshund homolog 1 gene diabetes mellitus familial young onset diabetes mellitus female gene gene expression genetic analysis genetic association genetic variability human human cell human tissue impaired glucose tolerance insulin release insulin resistance intron ischemic heart disease major clinical study male molecular pathology non insulin dependent diabetes mellitus peripheral blood mononuclear cell regulatory sequence single nucleotide polymorphism systolic blood pressure aged Asian continental ancestry group Cardiovascular Diseases Diabetes Mellitus, Type 2 genetic predisposition genetics genotype middle aged Prediabetic State single nucleotide polymorphism Aged Asian Continental Ancestry Group Cardiovascular Diseases Case-Control Studies Diabetes Mellitus, Type 2 Eye Proteins Female Genetic Predisposition to Disease Genome-Wide Association Study Genotype Humans Male Middle Aged Polymorphism, Single Nucleotide Prediabetic State Transcription Factors 10.1371/journal.pone.0084770 PLoS ONE 9 1 e84770 2020-03-26T06:44:59Z 2020-03-26T06:44:59Z 2014 Article Ma R.C.W., Lee H.M., Lam V.K.L., Tam C.H.T., Ho J.S.K., Zhao H.-L., Guan J., Kong A.P.S., Lau E., Zhang G., Luk A., Wang Y., Tsui S.K.W., Chan T.F., Hu C., Jia W.P., Park K.S., Lee H.K., Furuta H., Nanjo K., Shyong Tai E., Ng D.P.-K., Tang N.L.S., Woo J., Leung P.C., Xue H., Wong J., Leung P.S., Lau T.C.K., Tong P.C.Y., Xu G., Ng M.C.Y., So W.Y., Chan J.C.N. (2014). Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese. PLoS ONE 9 (1) : e84770. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0084770 19326203 https://scholarbank.nus.edu.sg/handle/10635/165964 Public Library of Science Unpaywall 20200320
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	insulin DACH1 protein, human eye protein transcription factor adult article Asian autopsy bioinformatics cardiovascular disease case control study Chinese cohort analysis controlled study coronary artery atherosclerosis Dachshund homolog 1 gene diabetes mellitus familial young onset diabetes mellitus female gene gene expression genetic analysis genetic association genetic variability human human cell human tissue impaired glucose tolerance insulin release insulin resistance intron ischemic heart disease major clinical study male molecular pathology non insulin dependent diabetes mellitus peripheral blood mononuclear cell regulatory sequence single nucleotide polymorphism systolic blood pressure aged Asian continental ancestry group Cardiovascular Diseases Diabetes Mellitus, Type 2 genetic predisposition genetics genotype middle aged Prediabetic State single nucleotide polymorphism Aged Asian Continental Ancestry Group Cardiovascular Diseases Case-Control Studies Diabetes Mellitus, Type 2 Eye Proteins Female Genetic Predisposition to Disease Genome-Wide Association Study Genotype Humans Male Middle Aged Polymorphism, Single Nucleotide Prediabetic State Transcription Factors
spellingShingle	insulin DACH1 protein, human eye protein transcription factor adult article Asian autopsy bioinformatics cardiovascular disease case control study Chinese cohort analysis controlled study coronary artery atherosclerosis Dachshund homolog 1 gene diabetes mellitus familial young onset diabetes mellitus female gene gene expression genetic analysis genetic association genetic variability human human cell human tissue impaired glucose tolerance insulin release insulin resistance intron ischemic heart disease major clinical study male molecular pathology non insulin dependent diabetes mellitus peripheral blood mononuclear cell regulatory sequence single nucleotide polymorphism systolic blood pressure aged Asian continental ancestry group Cardiovascular Diseases Diabetes Mellitus, Type 2 genetic predisposition genetics genotype middle aged Prediabetic State single nucleotide polymorphism Aged Asian Continental Ancestry Group Cardiovascular Diseases Case-Control Studies Diabetes Mellitus, Type 2 Eye Proteins Female Genetic Predisposition to Disease Genome-Wide Association Study Genotype Humans Male Middle Aged Polymorphism, Single Nucleotide Prediabetic State Transcription Factors Ma R.C.W. Lee H.M. Lam V.K.L. Tam C.H.T. Ho J.S.K. Zhao H.-L. Guan J. Kong A.P.S. Lau E. Zhang G. Luk A. Wang Y. Tsui S.K.W. Chan T.F. Hu C. Jia W.P. Park K.S. Lee H.K. Furuta H. Nanjo K. Shyong Tai E. Ng D.P.-K. Tang N.L.S. Woo J. Leung P.C. Xue H. Wong J. Leung P.S. Lau T.C.K. Tong P.C.Y. Xu G. Ng M.C.Y. So W.Y. Chan J.C.N. Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese
description	10.1371/journal.pone.0084770
author2	SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
author_facet	SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH Ma R.C.W. Lee H.M. Lam V.K.L. Tam C.H.T. Ho J.S.K. Zhao H.-L. Guan J. Kong A.P.S. Lau E. Zhang G. Luk A. Wang Y. Tsui S.K.W. Chan T.F. Hu C. Jia W.P. Park K.S. Lee H.K. Furuta H. Nanjo K. Shyong Tai E. Ng D.P.-K. Tang N.L.S. Woo J. Leung P.C. Xue H. Wong J. Leung P.S. Lau T.C.K. Tong P.C.Y. Xu G. Ng M.C.Y. So W.Y. Chan J.C.N.
format	Article
author	Ma R.C.W. Lee H.M. Lam V.K.L. Tam C.H.T. Ho J.S.K. Zhao H.-L. Guan J. Kong A.P.S. Lau E. Zhang G. Luk A. Wang Y. Tsui S.K.W. Chan T.F. Hu C. Jia W.P. Park K.S. Lee H.K. Furuta H. Nanjo K. Shyong Tai E. Ng D.P.-K. Tang N.L.S. Woo J. Leung P.C. Xue H. Wong J. Leung P.S. Lau T.C.K. Tong P.C.Y. Xu G. Ng M.C.Y. So W.Y. Chan J.C.N.
author_sort	Ma R.C.W.
title	Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese
title_short	Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese
title_full	Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese
title_fullStr	Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese
title_full_unstemmed	Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese
title_sort	familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of dach1 in chinese
publisher	Public Library of Science
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/165964
_version_	1781791996312027136

Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese

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