A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53

10.1186/s12915-017-0446-7

Saved in:

Bibliographic Details
Main Authors:	Wong, J.H, Alfatah, M, Sin, M.F, Sim, H.M, Verma, C.S, Lane, D.P, Arumugam, P
Other Authors:	PHARMACY
Format:	Article
Published:	2020
Subjects:	protein binding protein MDM2 protein p53 Saccharomyces cerevisiae protein binding site metabolism molecular library protein domain Saccharomyces cerevisiae two hybrid system Binding Sites Protein Binding Protein Interaction Domains and Motifs Proto-Oncogene Proteins c-mdm2 Saccharomyces cerevisiae Proteins Small Molecule Libraries Tumor Suppressor Protein p53 Two-Hybrid System Techniques
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/173762
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

id	sg-nus-scholar.10635-173762
record_format	dspace
spelling	sg-nus-scholar.10635-1737622024-04-18T03:07:02Z A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53 Wong, J.H Alfatah, M Sin, M.F Sim, H.M Verma, C.S Lane, D.P Arumugam, P PHARMACY BIOLOGY (NU) MEDICINE BIOLOGICAL SCIENCES protein binding protein MDM2 protein p53 Saccharomyces cerevisiae protein binding site metabolism molecular library protein domain Saccharomyces cerevisiae two hybrid system Binding Sites Protein Binding Protein Interaction Domains and Motifs Proto-Oncogene Proteins c-mdm2 Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Small Molecule Libraries Tumor Suppressor Protein p53 Two-Hybrid System Techniques 10.1186/s12915-017-0446-7 BMC Biology 15 1 108 2020-09-01T00:49:08Z 2020-09-01T00:49:08Z 2017 Article Wong, J.H, Alfatah, M, Sin, M.F, Sim, H.M, Verma, C.S, Lane, D.P, Arumugam, P (2017). A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53. BMC Biology 15 (1) : 108. ScholarBank@NUS Repository. https://doi.org/10.1186/s12915-017-0446-7 17417007 https://scholarbank.nus.edu.sg/handle/10635/173762 Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	protein binding protein MDM2 protein p53 Saccharomyces cerevisiae protein binding site metabolism molecular library protein domain Saccharomyces cerevisiae two hybrid system Binding Sites Protein Binding Protein Interaction Domains and Motifs Proto-Oncogene Proteins c-mdm2 Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Small Molecule Libraries Tumor Suppressor Protein p53 Two-Hybrid System Techniques
spellingShingle	protein binding protein MDM2 protein p53 Saccharomyces cerevisiae protein binding site metabolism molecular library protein domain Saccharomyces cerevisiae two hybrid system Binding Sites Protein Binding Protein Interaction Domains and Motifs Proto-Oncogene Proteins c-mdm2 Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Small Molecule Libraries Tumor Suppressor Protein p53 Two-Hybrid System Techniques Wong, J.H Alfatah, M Sin, M.F Sim, H.M Verma, C.S Lane, D.P Arumugam, P A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53
description	10.1186/s12915-017-0446-7
author2	PHARMACY
author_facet	PHARMACY Wong, J.H Alfatah, M Sin, M.F Sim, H.M Verma, C.S Lane, D.P Arumugam, P
format	Article
author	Wong, J.H Alfatah, M Sin, M.F Sim, H.M Verma, C.S Lane, D.P Arumugam, P
author_sort	Wong, J.H
title	A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53
title_short	A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53
title_full	A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53
title_fullStr	A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53
title_full_unstemmed	A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53
title_sort	yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative mdm2-binding site in p53
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/173762
_version_	1800914189178372096

A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53

Similar Items