A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53

• Main Authors: Wong, J.H, Alfatah, M, Sin, M.F, Sim, H.M, Verma, C.S, Lane, D.P, Arumugam, P
• Other Authors: PHARMACY
• Format: Article
• Published: 2020
• Subjects: protein binding; protein MDM2; protein p53; Saccharomyces cerevisiae protein; binding site; metabolism; molecular library; protein domain; Saccharomyces cerevisiae; two hybrid system; Binding Sites; Protein Binding; Protein Interaction Domains and Motifs; Proto-Oncogene Proteins c-mdm2; Saccharomyces cerevisiae Proteins; Small Molecule Libraries; Tumor Suppressor Protein p53; Two-Hybrid System Techniques
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/173762
• Institution: National University of Singapore

10.1186/s12915-017-0446-7