A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus

10.1186/s13073-017-0404-6

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Main Authors:	Kumar D., Puan K.J., Andiappan A.K., Lee B., Westerlaken G.H.A., Haase D., Melchiotti R., Li Z., Yusof N., Lum J., Koh G., Foo S., Yeong J., Alves A.C., Pekkanen J., Sun L.D., Irwanto A., Fairfax B.P., Naranbhai V., Common J.E.A., Tang M., Chuang C.K., Jarvelin M.-R., Knight J.C., Zhang X., Chew F.T., Prabhakar S., Jianjun L., Wang D.Y., Zolezzi F., Poidinger M., Lane E.B., Meyaard L., Rötzschke O.
Other Authors:	PHYSIOLOGY
Format:	Article
Published:	2020
Subjects:	bisulfite regulator protein signal inhibitory receptor on leukocyte 1 transcription factor PU 1 transcription factor YY1 unclassified drug immunoglobulin receptor SIRL1 protein, human adult Article atopic dermatitis binding affinity binding site chromatin immunoprecipitation cohort analysis controlled study CpG island disease activity disease association DNA methylation female flow cytometry gel mobility shift assay gene gene expression gene frequency gene function gene identification genetic association genotype human human cell male molecular docking molecular pathology monocyte promoter region protein determination protein DNA binding protein expression protein function sequence analysis single nucleotide polymorphism upregulation VSTM1 gene Asian continental ancestry group gene expression regulation genetics metabolism young adult Asian Continental Ancestry Group Dermatitis, Atopic DNA Methylation Female Gene Expression Regulation Humans Male Monocytes Polymorphism, Single Nucleotide Promoter Regions, Genetic Receptors, Immunologic Young Adult
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/173794
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1737942024-04-18T07:36:26Z A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus Kumar D. Puan K.J. Andiappan A.K. Lee B. Westerlaken G.H.A. Haase D. Melchiotti R. Li Z. Yusof N. Lum J. Koh G. Foo S. Yeong J. Alves A.C. Pekkanen J. Sun L.D. Irwanto A. Fairfax B.P. Naranbhai V. Common J.E.A. Tang M. Chuang C.K. Jarvelin M.-R. Knight J.C. Zhang X. Chew F.T. Prabhakar S. Jianjun L. Wang D.Y. Zolezzi F. Poidinger M. Lane E.B. Meyaard L. Rötzschke O. PHYSIOLOGY OTOLARYNGOLOGY BIOLOGY (NU) PATHOLOGY bisulfite regulator protein signal inhibitory receptor on leukocyte 1 transcription factor PU 1 transcription factor YY1 unclassified drug immunoglobulin receptor SIRL1 protein, human adult Article atopic dermatitis binding affinity binding site chromatin immunoprecipitation cohort analysis controlled study CpG island disease activity disease association DNA methylation female flow cytometry gel mobility shift assay gene gene expression gene frequency gene function gene identification genetic association genotype human human cell male molecular docking molecular pathology monocyte promoter region protein determination protein DNA binding protein expression protein function sequence analysis single nucleotide polymorphism upregulation VSTM1 gene Asian continental ancestry group atopic dermatitis gene expression regulation genetics metabolism young adult Asian Continental Ancestry Group Dermatitis, Atopic DNA Methylation Female Gene Expression Regulation Humans Male Monocytes Polymorphism, Single Nucleotide Promoter Regions, Genetic Receptors, Immunologic Young Adult 10.1186/s13073-017-0404-6 Genome Medicine 9 1 18 2020-09-01T00:55:59Z 2020-09-01T00:55:59Z 2017 Article Kumar D., Puan K.J., Andiappan A.K., Lee B., Westerlaken G.H.A., Haase D., Melchiotti R., Li Z., Yusof N., Lum J., Koh G., Foo S., Yeong J., Alves A.C., Pekkanen J., Sun L.D., Irwanto A., Fairfax B.P., Naranbhai V., Common J.E.A., Tang M., Chuang C.K., Jarvelin M.-R., Knight J.C., Zhang X., Chew F.T., Prabhakar S., Jianjun L., Wang D.Y., Zolezzi F., Poidinger M., Lane E.B., Meyaard L., Rötzschke O. (2017). A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus. Genome Medicine 9 (1) : 18. ScholarBank@NUS Repository. https://doi.org/10.1186/s13073-017-0404-6 1756994X https://scholarbank.nus.edu.sg/handle/10635/173794 Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	bisulfite regulator protein signal inhibitory receptor on leukocyte 1 transcription factor PU 1 transcription factor YY1 unclassified drug immunoglobulin receptor SIRL1 protein, human adult Article atopic dermatitis binding affinity binding site chromatin immunoprecipitation cohort analysis controlled study CpG island disease activity disease association DNA methylation female flow cytometry gel mobility shift assay gene gene expression gene frequency gene function gene identification genetic association genotype human human cell male molecular docking molecular pathology monocyte promoter region protein determination protein DNA binding protein expression protein function sequence analysis single nucleotide polymorphism upregulation VSTM1 gene Asian continental ancestry group atopic dermatitis gene expression regulation genetics metabolism young adult Asian Continental Ancestry Group Dermatitis, Atopic DNA Methylation Female Gene Expression Regulation Humans Male Monocytes Polymorphism, Single Nucleotide Promoter Regions, Genetic Receptors, Immunologic Young Adult
spellingShingle	bisulfite regulator protein signal inhibitory receptor on leukocyte 1 transcription factor PU 1 transcription factor YY1 unclassified drug immunoglobulin receptor SIRL1 protein, human adult Article atopic dermatitis binding affinity binding site chromatin immunoprecipitation cohort analysis controlled study CpG island disease activity disease association DNA methylation female flow cytometry gel mobility shift assay gene gene expression gene frequency gene function gene identification genetic association genotype human human cell male molecular docking molecular pathology monocyte promoter region protein determination protein DNA binding protein expression protein function sequence analysis single nucleotide polymorphism upregulation VSTM1 gene Asian continental ancestry group atopic dermatitis gene expression regulation genetics metabolism young adult Asian Continental Ancestry Group Dermatitis, Atopic DNA Methylation Female Gene Expression Regulation Humans Male Monocytes Polymorphism, Single Nucleotide Promoter Regions, Genetic Receptors, Immunologic Young Adult Kumar D. Puan K.J. Andiappan A.K. Lee B. Westerlaken G.H.A. Haase D. Melchiotti R. Li Z. Yusof N. Lum J. Koh G. Foo S. Yeong J. Alves A.C. Pekkanen J. Sun L.D. Irwanto A. Fairfax B.P. Naranbhai V. Common J.E.A. Tang M. Chuang C.K. Jarvelin M.-R. Knight J.C. Zhang X. Chew F.T. Prabhakar S. Jianjun L. Wang D.Y. Zolezzi F. Poidinger M. Lane E.B. Meyaard L. Rötzschke O. A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus
description	10.1186/s13073-017-0404-6
author2	PHYSIOLOGY
author_facet	PHYSIOLOGY Kumar D. Puan K.J. Andiappan A.K. Lee B. Westerlaken G.H.A. Haase D. Melchiotti R. Li Z. Yusof N. Lum J. Koh G. Foo S. Yeong J. Alves A.C. Pekkanen J. Sun L.D. Irwanto A. Fairfax B.P. Naranbhai V. Common J.E.A. Tang M. Chuang C.K. Jarvelin M.-R. Knight J.C. Zhang X. Chew F.T. Prabhakar S. Jianjun L. Wang D.Y. Zolezzi F. Poidinger M. Lane E.B. Meyaard L. Rötzschke O.
format	Article
author	Kumar D. Puan K.J. Andiappan A.K. Lee B. Westerlaken G.H.A. Haase D. Melchiotti R. Li Z. Yusof N. Lum J. Koh G. Foo S. Yeong J. Alves A.C. Pekkanen J. Sun L.D. Irwanto A. Fairfax B.P. Naranbhai V. Common J.E.A. Tang M. Chuang C.K. Jarvelin M.-R. Knight J.C. Zhang X. Chew F.T. Prabhakar S. Jianjun L. Wang D.Y. Zolezzi F. Poidinger M. Lane E.B. Meyaard L. Rötzschke O.
author_sort	Kumar D.
title	A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus
title_short	A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus
title_full	A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus
title_fullStr	A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus
title_full_unstemmed	A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus
title_sort	functional snp associated with atopic dermatitis controls cell type-specific methylation of the vstm1 gene locus
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/173794
_version_	1800914191558639616

A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus

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