Potential protective effects of ursolic acid against gamma irradiation-induced damage are mediated through the modulation of diverse inflammatory mediators

10.3389/fphar.2017.00352

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Main Authors: Wang H., Sim M.-K., Loke W.K., Chinnathambi A., Alharbi S.A., Tang F.R., Sethi G.
Other Authors: DEPT OF PHARMACOLOGY
Format: Article
Published: Frontiers Media S.A. 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/173879
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spelling sg-nus-scholar.10635-1738792023-11-01T07:53:11Z Potential protective effects of ursolic acid against gamma irradiation-induced damage are mediated through the modulation of diverse inflammatory mediators Wang H. Sim M.-K. Loke W.K. Chinnathambi A. Alharbi S.A. Tang F.R. Sethi G. DEPT OF PHARMACOLOGY cytokine free radical I kappa B kinase alpha immunoglobulin enhancer binding protein inflammatory mediator interleukin 1beta interleukin 6 nitrous oxide phosphoprotein reactive oxygen metabolite synaptotagmin I tumor necrosis factor unclassified drug ursolic acid animal cell animal experiment animal model animal tissue Article cell damage cell viability controlled study cytokine production cytotoxicity DNA binding DNA damage drug efficacy enzyme linked immunosorbent assay female gamma irradiation human human cell in vitro study in vivo study inflammation lipid peroxidation mouse nonhuman overall survival protein expression radiation dose radiation exposure radiation protection Western blotting whole body radiation 10.3389/fphar.2017.00352 Frontiers in Pharmacology 8 JUN 352 2020-09-01T08:04:12Z 2020-09-01T08:04:12Z 2017 Article Wang H., Sim M.-K., Loke W.K., Chinnathambi A., Alharbi S.A., Tang F.R., Sethi G. (2017). Potential protective effects of ursolic acid against gamma irradiation-induced damage are mediated through the modulation of diverse inflammatory mediators. Frontiers in Pharmacology 8 (JUN) : 352. ScholarBank@NUS Repository. https://doi.org/10.3389/fphar.2017.00352 16639812 https://scholarbank.nus.edu.sg/handle/10635/173879 Frontiers Media S.A. Unpaywall 20200831
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic cytokine
free radical
I kappa B kinase alpha
immunoglobulin enhancer binding protein
inflammatory mediator
interleukin 1beta
interleukin 6
nitrous oxide
phosphoprotein
reactive oxygen metabolite
synaptotagmin I
tumor necrosis factor
unclassified drug
ursolic acid
animal cell
animal experiment
animal model
animal tissue
Article
cell damage
cell viability
controlled study
cytokine production
cytotoxicity
DNA binding
DNA damage
drug efficacy
enzyme linked immunosorbent assay
female
gamma irradiation
human
human cell
in vitro study
in vivo study
inflammation
lipid peroxidation
mouse
nonhuman
overall survival
protein expression
radiation dose
radiation exposure
radiation protection
Western blotting
whole body radiation
spellingShingle cytokine
free radical
I kappa B kinase alpha
immunoglobulin enhancer binding protein
inflammatory mediator
interleukin 1beta
interleukin 6
nitrous oxide
phosphoprotein
reactive oxygen metabolite
synaptotagmin I
tumor necrosis factor
unclassified drug
ursolic acid
animal cell
animal experiment
animal model
animal tissue
Article
cell damage
cell viability
controlled study
cytokine production
cytotoxicity
DNA binding
DNA damage
drug efficacy
enzyme linked immunosorbent assay
female
gamma irradiation
human
human cell
in vitro study
in vivo study
inflammation
lipid peroxidation
mouse
nonhuman
overall survival
protein expression
radiation dose
radiation exposure
radiation protection
Western blotting
whole body radiation
Wang H.
Sim M.-K.
Loke W.K.
Chinnathambi A.
Alharbi S.A.
Tang F.R.
Sethi G.
Potential protective effects of ursolic acid against gamma irradiation-induced damage are mediated through the modulation of diverse inflammatory mediators
description 10.3389/fphar.2017.00352
author2 DEPT OF PHARMACOLOGY
author_facet DEPT OF PHARMACOLOGY
Wang H.
Sim M.-K.
Loke W.K.
Chinnathambi A.
Alharbi S.A.
Tang F.R.
Sethi G.
format Article
author Wang H.
Sim M.-K.
Loke W.K.
Chinnathambi A.
Alharbi S.A.
Tang F.R.
Sethi G.
author_sort Wang H.
title Potential protective effects of ursolic acid against gamma irradiation-induced damage are mediated through the modulation of diverse inflammatory mediators
title_short Potential protective effects of ursolic acid against gamma irradiation-induced damage are mediated through the modulation of diverse inflammatory mediators
title_full Potential protective effects of ursolic acid against gamma irradiation-induced damage are mediated through the modulation of diverse inflammatory mediators
title_fullStr Potential protective effects of ursolic acid against gamma irradiation-induced damage are mediated through the modulation of diverse inflammatory mediators
title_full_unstemmed Potential protective effects of ursolic acid against gamma irradiation-induced damage are mediated through the modulation of diverse inflammatory mediators
title_sort potential protective effects of ursolic acid against gamma irradiation-induced damage are mediated through the modulation of diverse inflammatory mediators
publisher Frontiers Media S.A.
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/173879
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