Potential protective effects of ursolic acid against gamma irradiation-induced damage are mediated through the modulation of diverse inflammatory mediators

• Main Authors: Wang H., Sim M.-K., Loke W.K., Chinnathambi A., Alharbi S.A., Tang F.R., Sethi G.
• Other Authors: DEPT OF PHARMACOLOGY
• Format: Article
• Published: Frontiers Media S.A. 2020
• Subjects: cytokine; free radical; I kappa B kinase alpha; immunoglobulin enhancer binding protein; inflammatory mediator; interleukin 1beta; interleukin 6; nitrous oxide; phosphoprotein; reactive oxygen metabolite; synaptotagmin I; tumor necrosis factor; unclassified drug; ursolic acid; animal cell; animal experiment; animal model; animal tissue; Article; cell damage; cell viability; controlled study; cytokine production; cytotoxicity; DNA binding; DNA damage; drug efficacy; enzyme linked immunosorbent assay; female; gamma irradiation; human; human cell; in vitro study; in vivo study; inflammation; lipid peroxidation; mouse; nonhuman; overall survival; protein expression; radiation dose; radiation exposure; radiation protection; Western blotting; whole body radiation
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/173879
• Institution: National University of Singapore

10.3389/fphar.2017.00352