Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease

10.1038/srep31652

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Main Authors:	Garcia-Miralles, M, Hong, X, Tan, L.J, Caron, N.S, Huang, Y, To, X.V, Lin, R.Y, Franciosi, S, Papapetropoulos, S, Hayardeny, L, Hayden, M.R, Chuang, K.-H, Pouladi, M.A
Other Authors:	DEAN'S OFFICE (MEDICINE)
Format:	Article
Published:	2020
Subjects:	interleukin 6 laquinimod quinolone derivative animal animal behavior blood corpus striatum diffusion tensor imaging disease model dose response drug effect female Huntington chorea male mouse pathology pathophysiology white matter Animals Behavior, Animal Corpus Striatum Diffusion Tensor Imaging Disease Models, Animal Dose-Response Relationship, Drug Female Huntington Disease Interleukin-6 Male Mice Quinolones White Matter
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/173996
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1739962024-04-18T03:04:12Z Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease Garcia-Miralles, M Hong, X Tan, L.J Caron, N.S Huang, Y To, X.V Lin, R.Y Franciosi, S Papapetropoulos, S Hayardeny, L Hayden, M.R Chuang, K.-H Pouladi, M.A DEAN'S OFFICE (MEDICINE) MEDICINE interleukin 6 laquinimod quinolone derivative animal animal behavior blood corpus striatum diffusion tensor imaging disease model dose response drug effect female Huntington chorea male mouse pathology pathophysiology white matter Animals Behavior, Animal Corpus Striatum Diffusion Tensor Imaging Disease Models, Animal Dose-Response Relationship, Drug Female Huntington Disease Interleukin-6 Male Mice Quinolones White Matter 10.1038/srep31652 Scientific Reports 6 31652 2020-09-02T06:51:09Z 2020-09-02T06:51:09Z 2016 Article Garcia-Miralles, M, Hong, X, Tan, L.J, Caron, N.S, Huang, Y, To, X.V, Lin, R.Y, Franciosi, S, Papapetropoulos, S, Hayardeny, L, Hayden, M.R, Chuang, K.-H, Pouladi, M.A (2016). Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease. Scientific Reports 6 : 31652. ScholarBank@NUS Repository. https://doi.org/10.1038/srep31652 20452322 https://scholarbank.nus.edu.sg/handle/10635/173996 Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	interleukin 6 laquinimod quinolone derivative animal animal behavior blood corpus striatum diffusion tensor imaging disease model dose response drug effect female Huntington chorea male mouse pathology pathophysiology white matter Animals Behavior, Animal Corpus Striatum Diffusion Tensor Imaging Disease Models, Animal Dose-Response Relationship, Drug Female Huntington Disease Interleukin-6 Male Mice Quinolones White Matter
spellingShingle	interleukin 6 laquinimod quinolone derivative animal animal behavior blood corpus striatum diffusion tensor imaging disease model dose response drug effect female Huntington chorea male mouse pathology pathophysiology white matter Animals Behavior, Animal Corpus Striatum Diffusion Tensor Imaging Disease Models, Animal Dose-Response Relationship, Drug Female Huntington Disease Interleukin-6 Male Mice Quinolones White Matter Garcia-Miralles, M Hong, X Tan, L.J Caron, N.S Huang, Y To, X.V Lin, R.Y Franciosi, S Papapetropoulos, S Hayardeny, L Hayden, M.R Chuang, K.-H Pouladi, M.A Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease
description	10.1038/srep31652
author2	DEAN'S OFFICE (MEDICINE)
author_facet	DEAN'S OFFICE (MEDICINE) Garcia-Miralles, M Hong, X Tan, L.J Caron, N.S Huang, Y To, X.V Lin, R.Y Franciosi, S Papapetropoulos, S Hayardeny, L Hayden, M.R Chuang, K.-H Pouladi, M.A
format	Article
author	Garcia-Miralles, M Hong, X Tan, L.J Caron, N.S Huang, Y To, X.V Lin, R.Y Franciosi, S Papapetropoulos, S Hayardeny, L Hayden, M.R Chuang, K.-H Pouladi, M.A
author_sort	Garcia-Miralles, M
title	Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease
title_short	Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease
title_full	Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease
title_fullStr	Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease
title_full_unstemmed	Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease
title_sort	laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the yac128 model of huntington disease
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/173996
_version_	1800914206310006784

Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease

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