Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration

10.18632/oncotarget.5615

Saved in:

Bibliographic Details
Main Authors:	Xiang W., Cheong J.K., Ang S.H., Teo B., Xu P., Asari K., Sun W.T., Than H., Bunte R.M., Virshup D.M., Chuah C.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2020
Subjects:	beta catenin casein kinase Ialpha CD34 antigen dasatinib pyrvinium embonate Wnt protein adenosine triphosphate antineoplastic agent casein kinase I animal experiment animal model animal tissue antineoplastic activity apoptosis Article cancer inhibition cell renewal chronic myeloid leukemia colony formation controlled study human human cell mitochondrial respiration mouse nonhuman protein protein interaction signal transduction stem cell tumor xenograft umbilical cord blood animal blast cell crisis cancer transplantation cell proliferation chemistry IC50 K-562 cell line Leukemia, Myelogenous, Chronic, BCR-ABL Positive metabolism mitochondrion phosphorylation RNA interference SCID mouse tumor cell line Adenosine Triphosphate Animals Antigens, CD34 Antineoplastic Combined Chemotherapy Protocols Apoptosis beta Catenin Blast Crisis Casein Kinase I Cell Line, Tumor Cell Proliferation Dasatinib Humans Inhibitory Concentration 50 K562 Cells Mice Mice, SCID Mitochondria Neoplasm Transplantation Phosphorylation Pyrvinium Compounds RNA Interference
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174134
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

id	sg-nus-scholar.10635-174134
record_format	dspace
spelling	sg-nus-scholar.10635-1741342023-09-20T08:54:15Z Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration Xiang W. Cheong J.K. Ang S.H. Teo B. Xu P. Asari K. Sun W.T. Than H. Bunte R.M. Virshup D.M. Chuah C. DUKE-NUS MEDICAL SCHOOL beta catenin casein kinase Ialpha CD34 antigen dasatinib pyrvinium embonate Wnt protein adenosine triphosphate antineoplastic agent beta catenin casein kinase I CD34 antigen dasatinib pyrvinium embonate animal experiment animal model animal tissue antineoplastic activity apoptosis Article cancer inhibition cell renewal chronic myeloid leukemia colony formation controlled study human human cell mitochondrial respiration mouse nonhuman protein protein interaction signal transduction stem cell tumor xenograft umbilical cord blood animal blast cell crisis cancer transplantation cell proliferation chemistry IC50 K-562 cell line Leukemia, Myelogenous, Chronic, BCR-ABL Positive metabolism mitochondrion phosphorylation RNA interference SCID mouse tumor cell line Adenosine Triphosphate Animals Antigens, CD34 Antineoplastic Combined Chemotherapy Protocols Apoptosis beta Catenin Blast Crisis Casein Kinase I Cell Line, Tumor Cell Proliferation Dasatinib Humans Inhibitory Concentration 50 K562 Cells Leukemia, Myelogenous, Chronic, BCR-ABL Positive Mice Mice, SCID Mitochondria Neoplasm Transplantation Phosphorylation Pyrvinium Compounds RNA Interference 10.18632/oncotarget.5615 Oncotarget 6 32 33769-33780 2020-09-03T10:36:07Z 2020-09-03T10:36:07Z 2015 Article Xiang W., Cheong J.K., Ang S.H., Teo B., Xu P., Asari K., Sun W.T., Than H., Bunte R.M., Virshup D.M., Chuah C. (2015). Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration. Oncotarget 6 (32) : 33769-33780. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.5615 19492553 https://scholarbank.nus.edu.sg/handle/10635/174134 Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	beta catenin casein kinase Ialpha CD34 antigen dasatinib pyrvinium embonate Wnt protein adenosine triphosphate antineoplastic agent beta catenin casein kinase I CD34 antigen dasatinib pyrvinium embonate animal experiment animal model animal tissue antineoplastic activity apoptosis Article cancer inhibition cell renewal chronic myeloid leukemia colony formation controlled study human human cell mitochondrial respiration mouse nonhuman protein protein interaction signal transduction stem cell tumor xenograft umbilical cord blood animal blast cell crisis cancer transplantation cell proliferation chemistry IC50 K-562 cell line Leukemia, Myelogenous, Chronic, BCR-ABL Positive metabolism mitochondrion phosphorylation RNA interference SCID mouse tumor cell line Adenosine Triphosphate Animals Antigens, CD34 Antineoplastic Combined Chemotherapy Protocols Apoptosis beta Catenin Blast Crisis Casein Kinase I Cell Line, Tumor Cell Proliferation Dasatinib Humans Inhibitory Concentration 50 K562 Cells Leukemia, Myelogenous, Chronic, BCR-ABL Positive Mice Mice, SCID Mitochondria Neoplasm Transplantation Phosphorylation Pyrvinium Compounds RNA Interference
spellingShingle	beta catenin casein kinase Ialpha CD34 antigen dasatinib pyrvinium embonate Wnt protein adenosine triphosphate antineoplastic agent beta catenin casein kinase I CD34 antigen dasatinib pyrvinium embonate animal experiment animal model animal tissue antineoplastic activity apoptosis Article cancer inhibition cell renewal chronic myeloid leukemia colony formation controlled study human human cell mitochondrial respiration mouse nonhuman protein protein interaction signal transduction stem cell tumor xenograft umbilical cord blood animal blast cell crisis cancer transplantation cell proliferation chemistry IC50 K-562 cell line Leukemia, Myelogenous, Chronic, BCR-ABL Positive metabolism mitochondrion phosphorylation RNA interference SCID mouse tumor cell line Adenosine Triphosphate Animals Antigens, CD34 Antineoplastic Combined Chemotherapy Protocols Apoptosis beta Catenin Blast Crisis Casein Kinase I Cell Line, Tumor Cell Proliferation Dasatinib Humans Inhibitory Concentration 50 K562 Cells Leukemia, Myelogenous, Chronic, BCR-ABL Positive Mice Mice, SCID Mitochondria Neoplasm Transplantation Phosphorylation Pyrvinium Compounds RNA Interference Xiang W. Cheong J.K. Ang S.H. Teo B. Xu P. Asari K. Sun W.T. Than H. Bunte R.M. Virshup D.M. Chuah C. Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration
description	10.18632/oncotarget.5615
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Xiang W. Cheong J.K. Ang S.H. Teo B. Xu P. Asari K. Sun W.T. Than H. Bunte R.M. Virshup D.M. Chuah C.
format	Article
author	Xiang W. Cheong J.K. Ang S.H. Teo B. Xu P. Asari K. Sun W.T. Than H. Bunte R.M. Virshup D.M. Chuah C.
author_sort	Xiang W.
title	Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration
title_short	Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration
title_full	Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration
title_fullStr	Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration
title_full_unstemmed	Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration
title_sort	pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/174134
_version_	1778169701464014848

Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration

Similar Items