RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells

RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells

10.18632/oncotarget.4654

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Bibliographic Details
Main Authors:	Brusgard, J.L, Choe, M, Chumsri, S, Renoud, K, MacKerell, A.D, Sudol, M, Passaniti, A
Other Authors:	PHYSIOLOGY
Format:	Article
Published:	2020
Subjects:	epidermal growth factor receptor 2 lapatinib neutralizing antibody transcription factor transcription factor RUNX2 transcription factor TAZ trastuzumab unclassified drug uvomorulin cadherin doxycycline protein binding signal peptide WWTR1 protein, human Article breast cancer breast cancer cell line cancer growth carcinogenicity cell nucleus cellular distribution controlled study drug targeting gene silencing human human cell overall survival protein domain protein expression protein function protein localization protein protein interaction signal transduction 3T3 cell line animal breast tumor drug effects gene expression regulation genetics MCF-7 cell line metabolism mouse multicellular spheroid pathology reverse transcription polymerase chain reaction RNA interference solubility Western blotting Animals Blotting, Western Breast Neoplasms Cadherins Core Binding Factor Alpha 1 Subunit Doxycycline Gene Expression Regulation, Neoplastic Humans Intracellular Signaling Peptides and Proteins MCF-7 Cells Mice NIH 3T3 Cells Protein Binding Receptor, ErbB-2 Reverse Transcriptase Polymerase Chain Reaction RNA Interference Signal Transduction Solubility Spheroids, Cellular Transcription Factors
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174137
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Institution:	National University of Singapore

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