RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells

• Main Authors: Brusgard, J.L, Choe, M, Chumsri, S, Renoud, K, MacKerell, A.D, Sudol, M, Passaniti, A
• Other Authors: PHYSIOLOGY
• Format: Article
• Published: 2020
• Subjects: epidermal growth factor receptor 2; lapatinib; neutralizing antibody; transcription factor; transcription factor RUNX2; transcription factor TAZ; trastuzumab; unclassified drug; uvomorulin; cadherin; doxycycline; protein binding; signal peptide; WWTR1 protein, human; Article; breast cancer; breast cancer cell line; cancer growth; carcinogenicity; cell nucleus; cellular distribution; controlled study; drug targeting; gene silencing; human; human cell; overall survival; protein domain; protein expression; protein function; protein localization; protein protein interaction; signal transduction; 3T3 cell line; animal; breast tumor; drug effects; gene expression regulation; genetics; MCF-7 cell line; metabolism; mouse; multicellular spheroid; pathology; reverse transcription polymerase chain reaction; RNA interference; solubility; Western blotting; Animals; Blotting, Western; Breast Neoplasms; Cadherins; Core Binding Factor Alpha 1 Subunit; Doxycycline; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; MCF-7 Cells; Mice; NIH 3T3 Cells; Protein Binding; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Solubility; Spheroids, Cellular; Transcription Factors
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174137
• Institution: National University of Singapore

10.18632/oncotarget.4654