Cystathionine ?-synthase inhibition is a potential therapeutic approach to treatment of ischemic injury

10.1177/1759091415578711

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Main Authors:	Chan, S.J, Chai, C, Lim, T.W, Yamamoto, M, Lo, E.H, Lai, M.K.P, Wong, P.T.H
Other Authors:	BIOCHEMISTRY
Format:	Article
Published:	2020
Subjects:	cystathionine beta synthase cysteine homocysteine hydrogen sulfide neuron specific nuclear protein aminooxyacetic acid enzyme inhibitor glucose animal cell animal experiment animal model animal tissue Article astrocyte cell death cell viability controlled study human human cell hypoxic ischemic encephalopathy immunofluorescence test male MTT assay nonhuman protein expression protein localization rat upregulation Western blotting animal antagonists and inhibitors brain brain ischemia cell culture cell hypoxia cell survival cerebral artery disease deficiency disease model drug effects genetics metabolism pathology PC12 cell line physiology Sprague Dawley rat tumor cell line Aminooxyacetic Acid Animals Astrocytes Brain Brain Ischemia Cell Hypoxia Cell Line, Tumor Cell Survival Cells, Cultured Cystathionine beta-Synthase Disease Models, Animal Enzyme Inhibitors Glucose Humans Hydrogen Sulfide Infarction, Middle Cerebral Artery PC12 Cells Rats Rats, Sprague-Dawley
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174141
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1741412024-04-22T03:16:22Z Cystathionine ?-synthase inhibition is a potential therapeutic approach to treatment of ischemic injury Chan, S.J Chai, C Lim, T.W Yamamoto, M Lo, E.H Lai, M.K.P Wong, P.T.H BIOCHEMISTRY PHARMACOLOGY DUKE-NUS MEDICAL SCHOOL cystathionine beta synthase cysteine homocysteine hydrogen sulfide neuron specific nuclear protein aminooxyacetic acid cystathionine beta synthase enzyme inhibitor glucose animal cell animal experiment animal model animal tissue Article astrocyte cell death cell viability controlled study human human cell hypoxic ischemic encephalopathy immunofluorescence test male MTT assay nonhuman protein expression protein localization rat upregulation Western blotting animal antagonists and inhibitors brain brain ischemia cell culture cell hypoxia cell survival cerebral artery disease deficiency disease model drug effects genetics metabolism pathology PC12 cell line physiology Sprague Dawley rat tumor cell line Aminooxyacetic Acid Animals Astrocytes Brain Brain Ischemia Cell Hypoxia Cell Line, Tumor Cell Survival Cells, Cultured Cystathionine beta-Synthase Disease Models, Animal Enzyme Inhibitors Glucose Humans Hydrogen Sulfide Infarction, Middle Cerebral Artery PC12 Cells Rats Rats, Sprague-Dawley 10.1177/1759091415578711 ASN Neuro 7 2 2020-09-03T10:37:27Z 2020-09-03T10:37:27Z 2015 Article Chan, S.J, Chai, C, Lim, T.W, Yamamoto, M, Lo, E.H, Lai, M.K.P, Wong, P.T.H (2015). Cystathionine ?-synthase inhibition is a potential therapeutic approach to treatment of ischemic injury. ASN Neuro 7 (2). ScholarBank@NUS Repository. https://doi.org/10.1177/1759091415578711 17590914 https://scholarbank.nus.edu.sg/handle/10635/174141 Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	cystathionine beta synthase cysteine homocysteine hydrogen sulfide neuron specific nuclear protein aminooxyacetic acid cystathionine beta synthase enzyme inhibitor glucose animal cell animal experiment animal model animal tissue Article astrocyte cell death cell viability controlled study human human cell hypoxic ischemic encephalopathy immunofluorescence test male MTT assay nonhuman protein expression protein localization rat upregulation Western blotting animal antagonists and inhibitors brain brain ischemia cell culture cell hypoxia cell survival cerebral artery disease deficiency disease model drug effects genetics metabolism pathology PC12 cell line physiology Sprague Dawley rat tumor cell line Aminooxyacetic Acid Animals Astrocytes Brain Brain Ischemia Cell Hypoxia Cell Line, Tumor Cell Survival Cells, Cultured Cystathionine beta-Synthase Disease Models, Animal Enzyme Inhibitors Glucose Humans Hydrogen Sulfide Infarction, Middle Cerebral Artery PC12 Cells Rats Rats, Sprague-Dawley
spellingShingle	cystathionine beta synthase cysteine homocysteine hydrogen sulfide neuron specific nuclear protein aminooxyacetic acid cystathionine beta synthase enzyme inhibitor glucose animal cell animal experiment animal model animal tissue Article astrocyte cell death cell viability controlled study human human cell hypoxic ischemic encephalopathy immunofluorescence test male MTT assay nonhuman protein expression protein localization rat upregulation Western blotting animal antagonists and inhibitors brain brain ischemia cell culture cell hypoxia cell survival cerebral artery disease deficiency disease model drug effects genetics metabolism pathology PC12 cell line physiology Sprague Dawley rat tumor cell line Aminooxyacetic Acid Animals Astrocytes Brain Brain Ischemia Cell Hypoxia Cell Line, Tumor Cell Survival Cells, Cultured Cystathionine beta-Synthase Disease Models, Animal Enzyme Inhibitors Glucose Humans Hydrogen Sulfide Infarction, Middle Cerebral Artery PC12 Cells Rats Rats, Sprague-Dawley Chan, S.J Chai, C Lim, T.W Yamamoto, M Lo, E.H Lai, M.K.P Wong, P.T.H Cystathionine ?-synthase inhibition is a potential therapeutic approach to treatment of ischemic injury
description	10.1177/1759091415578711
author2	BIOCHEMISTRY
author_facet	BIOCHEMISTRY Chan, S.J Chai, C Lim, T.W Yamamoto, M Lo, E.H Lai, M.K.P Wong, P.T.H
format	Article
author	Chan, S.J Chai, C Lim, T.W Yamamoto, M Lo, E.H Lai, M.K.P Wong, P.T.H
author_sort	Chan, S.J
title	Cystathionine ?-synthase inhibition is a potential therapeutic approach to treatment of ischemic injury
title_short	Cystathionine ?-synthase inhibition is a potential therapeutic approach to treatment of ischemic injury
title_full	Cystathionine ?-synthase inhibition is a potential therapeutic approach to treatment of ischemic injury
title_fullStr	Cystathionine ?-synthase inhibition is a potential therapeutic approach to treatment of ischemic injury
title_full_unstemmed	Cystathionine ?-synthase inhibition is a potential therapeutic approach to treatment of ischemic injury
title_sort	cystathionine ?-synthase inhibition is a potential therapeutic approach to treatment of ischemic injury
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/174141
_version_	1800914218565763072

Cystathionine ?-synthase inhibition is a potential therapeutic approach to treatment of ischemic injury

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