The over-expression of survivin enhances the chemotherapeutic efficacy of YM155 in human hepatocellular carcinoma

• Main Authors: Xia H., Chen J., Shi M., Deivasigamani A., Ooi L.L.P.J., Hui K.M.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: biological marker; phosphoprotein; sepantronium bromide; sorafenib; survivin; antineoplastic agent; Birc5 protein, mouse; imidazole derivative; inhibitor of apoptosis protein; naphthoquinone; repressor protein; animal experiment; animal model; animal tissue; apoptosis; Article; cancer tissue; carcinoma cell line; cell cycle arrest; cell proliferation; clinical article; continuous infusion; controlled study; DNA damage; drug response; human; human cell; human tissue; liver cell carcinoma; mouse; mouse model; nonhuman; prediction; protein expression; protein phosphorylation; tumor xenograft; animal; biosynthesis; Carcinoma, Hepatocellular; drug effects; drug screening; genetics; Liver Neoplasms; metabolism; nude mouse; pathology; tumor cell line; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; DNA Damage; Humans; Imidazoles; Inhibitor of Apoptosis Proteins; Mice; Mice, Nude; Naphthoquinones; Repressor Proteins; Xenograft Model Antitumor Assays
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174146
• Institution: National University of Singapore

10.18632/oncotarget.3337