SPHK1 regulates proliferation and survival responses in triplenegative breast cancer

10.18632/oncotarget.1874

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Main Authors:	Datta, A, Loo, S.Y, Huang, B, Wong, L, Tan, S.S.L, Tan, T.Z, Lee, S.-C, Thiery, J.P, Lim, Y.C, Yong, W.P, Lam, Y, Kumar, A.P, Yap, C.T
Other Authors:	PHYSIOLOGY
Format:	Article
Published:	2020
Subjects:	2,2 dimethyl(1 oxo 2 hexadecyn 1 yl) 1,1 dimethylethyl ester 3 oxazolidinecarboxylic acid docetaxel doxorubicin fluorouracil mitogen activated protein kinase 1 mitogen activated protein kinase 3 phosphotransferase inhibitor protein kinase B ski 5c small interfering RNA sphingosine kinase 1 unclassified drug phosphotransferase sphingosine kinase animal experiment animal model article cancer growth cancer prognosis cancer survival controlled study drug sensitization enzyme inhibition female gene silencing human human cell human tissue in vitro study mouse multiple cycle treatment nonhuman phase 2 clinical trial (topic) regulatory mechanism signal transduction triple negative breast cancer animal cell proliferation cell survival enzymology genetic transfection genetics MCF 7 cell line metabolism pathology physiology SCID mouse tumor cell line xenograft Animals Cell Line, Tumor Cell Proliferation Cell Survival Female Heterografts Humans MCF-7 Cells Mice Mice, SCID Phosphotransferases (Alcohol Group Acceptor) Transfection Triple Negative Breast Neoplasms
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174167
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-174167
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spelling	sg-nus-scholar.10635-1741672024-05-08T09:51:45Z SPHK1 regulates proliferation and survival responses in triplenegative breast cancer Datta, A Loo, S.Y Huang, B Wong, L Tan, S.S.L Tan, T.Z Lee, S.-C Thiery, J.P Lim, Y.C Yong, W.P Lam, Y Kumar, A.P Yap, C.T PHYSIOLOGY DEPT OF CHEMISTRY CANCER SCIENCE INSTITUTE OF SINGAPORE MEDICINE BIOCHEMISTRY PATHOLOGY PHARMACOLOGY 2,2 dimethyl(1 oxo 2 hexadecyn 1 yl) 1,1 dimethylethyl ester 3 oxazolidinecarboxylic acid docetaxel doxorubicin fluorouracil mitogen activated protein kinase 1 mitogen activated protein kinase 3 phosphotransferase inhibitor protein kinase B ski 5c small interfering RNA sphingosine kinase 1 unclassified drug phosphotransferase sphingosine kinase animal experiment animal model article cancer growth cancer prognosis cancer survival controlled study drug sensitization enzyme inhibition female gene silencing human human cell human tissue in vitro study mouse multiple cycle treatment nonhuman phase 2 clinical trial (topic) regulatory mechanism signal transduction triple negative breast cancer animal cell proliferation cell survival enzymology genetic transfection genetics MCF 7 cell line metabolism pathology physiology SCID mouse triple negative breast cancer tumor cell line xenograft Animals Cell Line, Tumor Cell Proliferation Cell Survival Female Heterografts Humans MCF-7 Cells Mice Mice, SCID Phosphotransferases (Alcohol Group Acceptor) Transfection Triple Negative Breast Neoplasms 10.18632/oncotarget.1874 Oncotarget 5 15 5920-5933 2020-09-03T10:41:59Z 2020-09-03T10:41:59Z 2014 Article Datta, A, Loo, S.Y, Huang, B, Wong, L, Tan, S.S.L, Tan, T.Z, Lee, S.-C, Thiery, J.P, Lim, Y.C, Yong, W.P, Lam, Y, Kumar, A.P, Yap, C.T (2014). SPHK1 regulates proliferation and survival responses in triplenegative breast cancer. Oncotarget 5 (15) : 5920-5933. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.1874 19492553 https://scholarbank.nus.edu.sg/handle/10635/174167 Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	2,2 dimethyl(1 oxo 2 hexadecyn 1 yl) 1,1 dimethylethyl ester 3 oxazolidinecarboxylic acid docetaxel doxorubicin fluorouracil mitogen activated protein kinase 1 mitogen activated protein kinase 3 phosphotransferase inhibitor protein kinase B ski 5c small interfering RNA sphingosine kinase 1 unclassified drug phosphotransferase sphingosine kinase animal experiment animal model article cancer growth cancer prognosis cancer survival controlled study drug sensitization enzyme inhibition female gene silencing human human cell human tissue in vitro study mouse multiple cycle treatment nonhuman phase 2 clinical trial (topic) regulatory mechanism signal transduction triple negative breast cancer animal cell proliferation cell survival enzymology genetic transfection genetics MCF 7 cell line metabolism pathology physiology SCID mouse triple negative breast cancer tumor cell line xenograft Animals Cell Line, Tumor Cell Proliferation Cell Survival Female Heterografts Humans MCF-7 Cells Mice Mice, SCID Phosphotransferases (Alcohol Group Acceptor) Transfection Triple Negative Breast Neoplasms
spellingShingle	2,2 dimethyl(1 oxo 2 hexadecyn 1 yl) 1,1 dimethylethyl ester 3 oxazolidinecarboxylic acid docetaxel doxorubicin fluorouracil mitogen activated protein kinase 1 mitogen activated protein kinase 3 phosphotransferase inhibitor protein kinase B ski 5c small interfering RNA sphingosine kinase 1 unclassified drug phosphotransferase sphingosine kinase animal experiment animal model article cancer growth cancer prognosis cancer survival controlled study drug sensitization enzyme inhibition female gene silencing human human cell human tissue in vitro study mouse multiple cycle treatment nonhuman phase 2 clinical trial (topic) regulatory mechanism signal transduction triple negative breast cancer animal cell proliferation cell survival enzymology genetic transfection genetics MCF 7 cell line metabolism pathology physiology SCID mouse triple negative breast cancer tumor cell line xenograft Animals Cell Line, Tumor Cell Proliferation Cell Survival Female Heterografts Humans MCF-7 Cells Mice Mice, SCID Phosphotransferases (Alcohol Group Acceptor) Transfection Triple Negative Breast Neoplasms Datta, A Loo, S.Y Huang, B Wong, L Tan, S.S.L Tan, T.Z Lee, S.-C Thiery, J.P Lim, Y.C Yong, W.P Lam, Y Kumar, A.P Yap, C.T SPHK1 regulates proliferation and survival responses in triplenegative breast cancer
description	10.18632/oncotarget.1874
author2	PHYSIOLOGY
author_facet	PHYSIOLOGY Datta, A Loo, S.Y Huang, B Wong, L Tan, S.S.L Tan, T.Z Lee, S.-C Thiery, J.P Lim, Y.C Yong, W.P Lam, Y Kumar, A.P Yap, C.T
format	Article
author	Datta, A Loo, S.Y Huang, B Wong, L Tan, S.S.L Tan, T.Z Lee, S.-C Thiery, J.P Lim, Y.C Yong, W.P Lam, Y Kumar, A.P Yap, C.T
author_sort	Datta, A
title	SPHK1 regulates proliferation and survival responses in triplenegative breast cancer
title_short	SPHK1 regulates proliferation and survival responses in triplenegative breast cancer
title_full	SPHK1 regulates proliferation and survival responses in triplenegative breast cancer
title_fullStr	SPHK1 regulates proliferation and survival responses in triplenegative breast cancer
title_full_unstemmed	SPHK1 regulates proliferation and survival responses in triplenegative breast cancer
title_sort	sphk1 regulates proliferation and survival responses in triplenegative breast cancer
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/174167
_version_	1800914220770918400

SPHK1 regulates proliferation and survival responses in triplenegative breast cancer

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