Expression of two non-mutated genetic elements is sufficient to stimulate oncogenic transformation of human mammary epithelial cells

• Main Authors: Pandey, V, Zhang, M, You, M, Zhang, W, Chen, R, Ma, L, Wu, Z.-S, Zhu, T, Xu, X.Q, Lobie, P.E
• Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: cyclin D1; doxorubicin; protein bcl 2; small interfering RNA; STAT3 protein; trefoil factor 3; acinar cell; anchorage independent growth; animal experiment; animal model; Article; breast carcinoma; breast epithelium cell; carcinogenesis; carcinogenicity; cell proliferation; cell survival; cell viability; cohort analysis; controlled study; gene expression; HMEC-hTERT cell line; human; human cell; immortalized cell line; immune deficiency; major clinical study; MCF-10AT cell line; MCF-12A cell line; mouse; nonhuman; oncogene; phenotype; priority journal; protein expression; protein function; regulatory mechanism; transcription regulation; upregulation
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174191
• Institution: National University of Singapore

10.1038/s41419-018-1177-6