A systematic approach to the development of a safe live attenuated Zika vaccine
10.1038/s41467-018-03337-2
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2020
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sg-nus-scholar.10635-1742342020-09-06T15:54:05Z A systematic approach to the development of a safe live attenuated Zika vaccine Kwek, S.S Watanabe, S Chan, K.R Ong, E.Z Tan, H.C Ng, W.C Nguyen, M.T.X Gan, E.S Zhang, S.L Chan, K.W.K Tan, J.H Sessions, O.M Manuel, M Pompon, J Chua, C Hazirah, S Tryggvason, K Vasudevan, S.G Ooi, E.E DUKE-NUS MEDICAL SCHOOL interferon regulatory factor 3 live vaccine Zika virus vaccine live vaccine virus vaccine cell immunity rodent strategic approach vaccine vertical transmission yellow fever Zika virus disease adult animal cell animal experiment animal model animal tissue Article B lymphocyte controlled study dendritic cell drug efficacy drug mechanism drug safety embryo female fetus gene activation genetic variability genomic instability human human cell in vitro propagation infection risk innate immunity male mouse mouse model next generation sequencing nonhuman single nucleotide polymorphism T lymphocyte umbilical vein endothelial cell vaccine immunogenicity Vero cell line vertical transmission virus culture virus mutation virus plaque virus transmission whole genome sequencing wild type Zika fever Zika virus Aedes animal evaluation study genetics growth, development and aging immunological technique immunology virology Zika fever Flavivirus Human immunodeficiency virus 1 Zika virus Aedes Animals Dendritic Cells Humans Immunologic Techniques Mice Vaccines, Attenuated Viral Vaccines Zika Virus Zika Virus Infection 10.1038/s41467-018-03337-2 Nature Communications 9 1 1031 2020-09-04T01:51:39Z 2020-09-04T01:51:39Z 2018 Article Kwek, S.S, Watanabe, S, Chan, K.R, Ong, E.Z, Tan, H.C, Ng, W.C, Nguyen, M.T.X, Gan, E.S, Zhang, S.L, Chan, K.W.K, Tan, J.H, Sessions, O.M, Manuel, M, Pompon, J, Chua, C, Hazirah, S, Tryggvason, K, Vasudevan, S.G, Ooi, E.E (2018). A systematic approach to the development of a safe live attenuated Zika vaccine. Nature Communications 9 (1) : 1031. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-018-03337-2 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/174234 Nature Publishing Group Unpaywall 20200831 |
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interferon regulatory factor 3 live vaccine Zika virus vaccine live vaccine virus vaccine cell immunity rodent strategic approach vaccine vertical transmission yellow fever Zika virus disease adult animal cell animal experiment animal model animal tissue Article B lymphocyte controlled study dendritic cell drug efficacy drug mechanism drug safety embryo female fetus gene activation genetic variability genomic instability human human cell in vitro propagation infection risk innate immunity male mouse mouse model next generation sequencing nonhuman single nucleotide polymorphism T lymphocyte umbilical vein endothelial cell vaccine immunogenicity Vero cell line vertical transmission virus culture virus mutation virus plaque virus transmission whole genome sequencing wild type Zika fever Zika virus Aedes animal evaluation study genetics growth, development and aging immunological technique immunology virology Zika fever Flavivirus Human immunodeficiency virus 1 Zika virus Aedes Animals Dendritic Cells Humans Immunologic Techniques Mice Vaccines, Attenuated Viral Vaccines Zika Virus Zika Virus Infection |
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interferon regulatory factor 3 live vaccine Zika virus vaccine live vaccine virus vaccine cell immunity rodent strategic approach vaccine vertical transmission yellow fever Zika virus disease adult animal cell animal experiment animal model animal tissue Article B lymphocyte controlled study dendritic cell drug efficacy drug mechanism drug safety embryo female fetus gene activation genetic variability genomic instability human human cell in vitro propagation infection risk innate immunity male mouse mouse model next generation sequencing nonhuman single nucleotide polymorphism T lymphocyte umbilical vein endothelial cell vaccine immunogenicity Vero cell line vertical transmission virus culture virus mutation virus plaque virus transmission whole genome sequencing wild type Zika fever Zika virus Aedes animal evaluation study genetics growth, development and aging immunological technique immunology virology Zika fever Flavivirus Human immunodeficiency virus 1 Zika virus Aedes Animals Dendritic Cells Humans Immunologic Techniques Mice Vaccines, Attenuated Viral Vaccines Zika Virus Zika Virus Infection Kwek, S.S Watanabe, S Chan, K.R Ong, E.Z Tan, H.C Ng, W.C Nguyen, M.T.X Gan, E.S Zhang, S.L Chan, K.W.K Tan, J.H Sessions, O.M Manuel, M Pompon, J Chua, C Hazirah, S Tryggvason, K Vasudevan, S.G Ooi, E.E A systematic approach to the development of a safe live attenuated Zika vaccine |
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10.1038/s41467-018-03337-2 |
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DUKE-NUS MEDICAL SCHOOL |
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DUKE-NUS MEDICAL SCHOOL Kwek, S.S Watanabe, S Chan, K.R Ong, E.Z Tan, H.C Ng, W.C Nguyen, M.T.X Gan, E.S Zhang, S.L Chan, K.W.K Tan, J.H Sessions, O.M Manuel, M Pompon, J Chua, C Hazirah, S Tryggvason, K Vasudevan, S.G Ooi, E.E |
format |
Article |
author |
Kwek, S.S Watanabe, S Chan, K.R Ong, E.Z Tan, H.C Ng, W.C Nguyen, M.T.X Gan, E.S Zhang, S.L Chan, K.W.K Tan, J.H Sessions, O.M Manuel, M Pompon, J Chua, C Hazirah, S Tryggvason, K Vasudevan, S.G Ooi, E.E |
author_sort |
Kwek, S.S |
title |
A systematic approach to the development of a safe live attenuated Zika vaccine |
title_short |
A systematic approach to the development of a safe live attenuated Zika vaccine |
title_full |
A systematic approach to the development of a safe live attenuated Zika vaccine |
title_fullStr |
A systematic approach to the development of a safe live attenuated Zika vaccine |
title_full_unstemmed |
A systematic approach to the development of a safe live attenuated Zika vaccine |
title_sort |
systematic approach to the development of a safe live attenuated zika vaccine |
publisher |
Nature Publishing Group |
publishDate |
2020 |
url |
https://scholarbank.nus.edu.sg/handle/10635/174234 |
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1681101719725932544 |