Knockdown of POLA2 increases gemcitabine resistance in lung cancer cells

10.1186/s12864-016-3322-x

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Main Authors:	Koh, V, Kwan, H.Y, Tan, W.L, Mah, T.L, Yong, W.P
Other Authors:	CANCER SCIENCE INSTITUTE OF SINGAPORE
Format:	Article
Published:	BioMed Central Ltd. 2020
Subjects:	DNA directed DNA polymerase alpha gemcitabine small interfering RNA antineoplastic antimetabolite deoxycytidine DNA directed DNA polymerase beta Article cancer resistance cell viability chemosensitivity concentration response controlled study drug effect gene function gene silencing genetic association genetic conservation genetic transfection H1299 cell line H1650 cell line human human cell lung cancer cell line non small cell lung cancer PC9 cell line POLA2 gene sequence analysis single nucleotide polymorphism wild type analogs and derivatives biology chromosomal mapping drug resistance epistasis gene expression regulation genetics lung tumor procedures tumor cell line Antimetabolites, Antineoplastic Cell Line, Tumor Chromosome Mapping Computational Biology Deoxycytidine DNA Polymerase I Drug Resistance, Neoplasm Epistasis, Genetic Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Humans Lung Neoplasms Polymorphism, Single Nucleotide
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174242
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-174242
record_format	dspace
spelling	sg-nus-scholar.10635-1742422023-11-01T08:05:37Z Knockdown of POLA2 increases gemcitabine resistance in lung cancer cells Koh, V Kwan, H.Y Tan, W.L Mah, T.L Yong, W.P CANCER SCIENCE INSTITUTE OF SINGAPORE DNA directed DNA polymerase alpha gemcitabine small interfering RNA antineoplastic antimetabolite deoxycytidine DNA directed DNA polymerase beta gemcitabine Article cancer resistance cell viability chemosensitivity concentration response controlled study drug effect gene function gene silencing genetic association genetic conservation genetic transfection H1299 cell line H1650 cell line human human cell lung cancer cell line non small cell lung cancer PC9 cell line POLA2 gene sequence analysis single nucleotide polymorphism wild type analogs and derivatives biology chromosomal mapping drug resistance epistasis gene expression regulation gene silencing genetics lung tumor procedures tumor cell line Antimetabolites, Antineoplastic Cell Line, Tumor Chromosome Mapping Computational Biology Deoxycytidine DNA Polymerase I Drug Resistance, Neoplasm Epistasis, Genetic Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Humans Lung Neoplasms Polymorphism, Single Nucleotide 10.1186/s12864-016-3322-x BMC Genomics 17 1029 2020-09-04T02:01:49Z 2020-09-04T02:01:49Z 2016 Article Koh, V, Kwan, H.Y, Tan, W.L, Mah, T.L, Yong, W.P (2016). Knockdown of POLA2 increases gemcitabine resistance in lung cancer cells. BMC Genomics 17 : 1029. ScholarBank@NUS Repository. https://doi.org/10.1186/s12864-016-3322-x 14712164 https://scholarbank.nus.edu.sg/handle/10635/174242 BioMed Central Ltd. Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	DNA directed DNA polymerase alpha gemcitabine small interfering RNA antineoplastic antimetabolite deoxycytidine DNA directed DNA polymerase beta gemcitabine Article cancer resistance cell viability chemosensitivity concentration response controlled study drug effect gene function gene silencing genetic association genetic conservation genetic transfection H1299 cell line H1650 cell line human human cell lung cancer cell line non small cell lung cancer PC9 cell line POLA2 gene sequence analysis single nucleotide polymorphism wild type analogs and derivatives biology chromosomal mapping drug resistance epistasis gene expression regulation gene silencing genetics lung tumor procedures tumor cell line Antimetabolites, Antineoplastic Cell Line, Tumor Chromosome Mapping Computational Biology Deoxycytidine DNA Polymerase I Drug Resistance, Neoplasm Epistasis, Genetic Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Humans Lung Neoplasms Polymorphism, Single Nucleotide
spellingShingle	DNA directed DNA polymerase alpha gemcitabine small interfering RNA antineoplastic antimetabolite deoxycytidine DNA directed DNA polymerase beta gemcitabine Article cancer resistance cell viability chemosensitivity concentration response controlled study drug effect gene function gene silencing genetic association genetic conservation genetic transfection H1299 cell line H1650 cell line human human cell lung cancer cell line non small cell lung cancer PC9 cell line POLA2 gene sequence analysis single nucleotide polymorphism wild type analogs and derivatives biology chromosomal mapping drug resistance epistasis gene expression regulation gene silencing genetics lung tumor procedures tumor cell line Antimetabolites, Antineoplastic Cell Line, Tumor Chromosome Mapping Computational Biology Deoxycytidine DNA Polymerase I Drug Resistance, Neoplasm Epistasis, Genetic Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Humans Lung Neoplasms Polymorphism, Single Nucleotide Koh, V Kwan, H.Y Tan, W.L Mah, T.L Yong, W.P Knockdown of POLA2 increases gemcitabine resistance in lung cancer cells
description	10.1186/s12864-016-3322-x
author2	CANCER SCIENCE INSTITUTE OF SINGAPORE
author_facet	CANCER SCIENCE INSTITUTE OF SINGAPORE Koh, V Kwan, H.Y Tan, W.L Mah, T.L Yong, W.P
format	Article
author	Koh, V Kwan, H.Y Tan, W.L Mah, T.L Yong, W.P
author_sort	Koh, V
title	Knockdown of POLA2 increases gemcitabine resistance in lung cancer cells
title_short	Knockdown of POLA2 increases gemcitabine resistance in lung cancer cells
title_full	Knockdown of POLA2 increases gemcitabine resistance in lung cancer cells
title_fullStr	Knockdown of POLA2 increases gemcitabine resistance in lung cancer cells
title_full_unstemmed	Knockdown of POLA2 increases gemcitabine resistance in lung cancer cells
title_sort	knockdown of pola2 increases gemcitabine resistance in lung cancer cells
publisher	BioMed Central Ltd.
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/174242
_version_	1781792183686266880

Knockdown of POLA2 increases gemcitabine resistance in lung cancer cells

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