HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis

10.1038/s41467-017-02601-1

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Main Authors:	Yan, T, Ooi, W.F, Qamra, A, Cheung, A, Ma, D, Sundaram, G.M, Xu, C, Xing, M, Poon, L, Wang, J, Loh, Y.P, Ho, J.H.J, Ng, J.J.Q, Ramlee, M.K, Aswad, L, Rozen, S.G, Ghosh, S, Bard, F.A, Sampath, P, Tergaonkar, V, Davies, J.O.J, Hughes, J.R, Goh, E, Bi, X, Fullwood, M.J, Tan, P, Li, S
Other Authors:	CANCER SCIENCE INSTITUTE OF SINGAPORE
Published:	Nature Publishing Group 2020
Subjects:	microRNA microRNA 615 3p unclassified drug homeodomain protein HOXC5 protein, human MIRN615 microRNA, human telomerase TERT protein, human aging cancer cell differentiation embryonic development gene expression genome inhibition physiology primate tumor 3' untranslated region 5' untranslated region Article carcinogenesis cell differentiation enhancer region gene hoxc5 gene human human cell intron reverse transcription polymerase chain reaction animal biosynthesis cell transformation genetics HEK293 cell line HeLa cell line Hep-G2 cell line MCF-7 cell line mouse neoplasm pathology promoter region tumor cell line Mammalia Primates 3' Untranslated Regions 5' Untranslated Regions Animals Cell Differentiation Cell Line, Tumor Cell Transformation, Neoplastic Enhancer Elements, Genetic HEK293 Cells HeLa Cells Hep G2 Cells Homeodomain Proteins Humans MCF-7 Cells Mice MicroRNAs Neoplasms Promoter Regions, Genetic Telomerase
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174312
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1743122021-12-14T13:05:54Z HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis Yan, T Ooi, W.F Qamra, A Cheung, A Ma, D Sundaram, G.M Xu, C Xing, M Poon, L Wang, J Loh, Y.P Ho, J.H.J Ng, J.J.Q Ramlee, M.K Aswad, L Rozen, S.G Ghosh, S Bard, F.A Sampath, P Tergaonkar, V Davies, J.O.J Hughes, J.R Goh, E Bi, X Fullwood, M.J Tan, P Li, S CANCER SCIENCE INSTITUTE OF SINGAPORE DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL) DUKE-NUS MEDICAL SCHOOL microRNA microRNA 615 3p unclassified drug homeodomain protein HOXC5 protein, human microRNA MIRN615 microRNA, human telomerase TERT protein, human aging cancer cell differentiation embryonic development gene expression genome inhibition physiology primate tumor 3' untranslated region 5' untranslated region Article carcinogenesis cell differentiation enhancer region gene hoxc5 gene human human cell intron reverse transcription polymerase chain reaction animal biosynthesis cell transformation genetics HEK293 cell line HeLa cell line Hep-G2 cell line MCF-7 cell line mouse neoplasm pathology promoter region tumor cell line Mammalia Primates 3' Untranslated Regions 5' Untranslated Regions Animals Cell Differentiation Cell Line, Tumor Cell Transformation, Neoplastic Enhancer Elements, Genetic HEK293 Cells HeLa Cells Hep G2 Cells Homeodomain Proteins Humans MCF-7 Cells Mice MicroRNAs Neoplasms Promoter Regions, Genetic Telomerase 10.1038/s41467-017-02601-1 Nature Communications 9 1 100 2020-09-04T02:17:44Z 2020-09-04T02:17:44Z 2018 Yan, T, Ooi, W.F, Qamra, A, Cheung, A, Ma, D, Sundaram, G.M, Xu, C, Xing, M, Poon, L, Wang, J, Loh, Y.P, Ho, J.H.J, Ng, J.J.Q, Ramlee, M.K, Aswad, L, Rozen, S.G, Ghosh, S, Bard, F.A, Sampath, P, Tergaonkar, V, Davies, J.O.J, Hughes, J.R, Goh, E, Bi, X, Fullwood, M.J, Tan, P, Li, S (2018). HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis. Nature Communications 9 (1) : 100. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-017-02601-1 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/174312 Nature Publishing Group Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	microRNA microRNA 615 3p unclassified drug homeodomain protein HOXC5 protein, human microRNA MIRN615 microRNA, human telomerase TERT protein, human aging cancer cell differentiation embryonic development gene expression genome inhibition physiology primate tumor 3' untranslated region 5' untranslated region Article carcinogenesis cell differentiation enhancer region gene hoxc5 gene human human cell intron reverse transcription polymerase chain reaction animal biosynthesis cell transformation genetics HEK293 cell line HeLa cell line Hep-G2 cell line MCF-7 cell line mouse neoplasm pathology promoter region tumor cell line Mammalia Primates 3' Untranslated Regions 5' Untranslated Regions Animals Cell Differentiation Cell Line, Tumor Cell Transformation, Neoplastic Enhancer Elements, Genetic HEK293 Cells HeLa Cells Hep G2 Cells Homeodomain Proteins Humans MCF-7 Cells Mice MicroRNAs Neoplasms Promoter Regions, Genetic Telomerase
spellingShingle	microRNA microRNA 615 3p unclassified drug homeodomain protein HOXC5 protein, human microRNA MIRN615 microRNA, human telomerase TERT protein, human aging cancer cell differentiation embryonic development gene expression genome inhibition physiology primate tumor 3' untranslated region 5' untranslated region Article carcinogenesis cell differentiation enhancer region gene hoxc5 gene human human cell intron reverse transcription polymerase chain reaction animal biosynthesis cell transformation genetics HEK293 cell line HeLa cell line Hep-G2 cell line MCF-7 cell line mouse neoplasm pathology promoter region tumor cell line Mammalia Primates 3' Untranslated Regions 5' Untranslated Regions Animals Cell Differentiation Cell Line, Tumor Cell Transformation, Neoplastic Enhancer Elements, Genetic HEK293 Cells HeLa Cells Hep G2 Cells Homeodomain Proteins Humans MCF-7 Cells Mice MicroRNAs Neoplasms Promoter Regions, Genetic Telomerase Yan, T Ooi, W.F Qamra, A Cheung, A Ma, D Sundaram, G.M Xu, C Xing, M Poon, L Wang, J Loh, Y.P Ho, J.H.J Ng, J.J.Q Ramlee, M.K Aswad, L Rozen, S.G Ghosh, S Bard, F.A Sampath, P Tergaonkar, V Davies, J.O.J Hughes, J.R Goh, E Bi, X Fullwood, M.J Tan, P Li, S HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis
description	10.1038/s41467-017-02601-1
author2	CANCER SCIENCE INSTITUTE OF SINGAPORE
author_facet	CANCER SCIENCE INSTITUTE OF SINGAPORE Yan, T Ooi, W.F Qamra, A Cheung, A Ma, D Sundaram, G.M Xu, C Xing, M Poon, L Wang, J Loh, Y.P Ho, J.H.J Ng, J.J.Q Ramlee, M.K Aswad, L Rozen, S.G Ghosh, S Bard, F.A Sampath, P Tergaonkar, V Davies, J.O.J Hughes, J.R Goh, E Bi, X Fullwood, M.J Tan, P Li, S
author	Yan, T Ooi, W.F Qamra, A Cheung, A Ma, D Sundaram, G.M Xu, C Xing, M Poon, L Wang, J Loh, Y.P Ho, J.H.J Ng, J.J.Q Ramlee, M.K Aswad, L Rozen, S.G Ghosh, S Bard, F.A Sampath, P Tergaonkar, V Davies, J.O.J Hughes, J.R Goh, E Bi, X Fullwood, M.J Tan, P Li, S
author_sort	Yan, T
title	HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis
title_short	HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis
title_full	HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis
title_fullStr	HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis
title_full_unstemmed	HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis
title_sort	hoxc5 and mir-615-3p target newly evolved genomic regions to repress htert and inhibit tumorigenesis
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/174312
_version_	1720446949024333824

HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis

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