Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity

10.1038/s41598-018-20305-4

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Main Authors:	Lum, F.-M, Couderc, T, Chia, B.-S, Ong, R.-Y, Her, Z, Chow, A, Leo, Y.-S, Kam, Y.-W, Rénia, L, Lecuit, M, Ng, L.F.P
Other Authors:	SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	Fc receptor Fc receptor IIa gamma interferon neutralizing antibody virus antibody animal arthralgia C57BL mouse cell culture chikungunya Chikungunya virus human immunology knockout mouse macrophage metabolism mouse pathology physiology severity of illness index virology virus load virus replication Animals Antibodies, Neutralizing Antibodies, Viral Arthralgia Cells, Cultured Chikungunya Fever Humans Interferon-gamma Macrophages Mice Mice, Inbred C57BL Mice, Knockout Receptors, IgG Severity of Illness Index Viral Load Virus Replication
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174342
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1743422024-04-22T03:10:34Z Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity Lum, F.-M Couderc, T Chia, B.-S Ong, R.-Y Her, Z Chow, A Leo, Y.-S Kam, Y.-W Rénia, L Lecuit, M Ng, L.F.P SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH MICROBIOLOGY AND IMMUNOLOGY BIOCHEMISTRY Fc receptor Fc receptor IIa gamma interferon neutralizing antibody virus antibody animal arthralgia C57BL mouse cell culture chikungunya Chikungunya virus human immunology knockout mouse macrophage metabolism mouse pathology physiology severity of illness index virology virus load virus replication Animals Antibodies, Neutralizing Antibodies, Viral Arthralgia Cells, Cultured Chikungunya Fever Chikungunya virus Humans Interferon-gamma Macrophages Mice Mice, Inbred C57BL Mice, Knockout Receptors, IgG Severity of Illness Index Viral Load Virus Replication 10.1038/s41598-018-20305-4 Scientific Reports 8 1 1860 2020-09-04T02:19:36Z 2020-09-04T02:19:36Z 2018 Article Lum, F.-M, Couderc, T, Chia, B.-S, Ong, R.-Y, Her, Z, Chow, A, Leo, Y.-S, Kam, Y.-W, Rénia, L, Lecuit, M, Ng, L.F.P (2018). Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity. Scientific Reports 8 (1) : 1860. ScholarBank@NUS Repository. https://doi.org/10.1038/s41598-018-20305-4 2045-2322 https://scholarbank.nus.edu.sg/handle/10635/174342 Nature Publishing Group Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	Fc receptor Fc receptor IIa gamma interferon neutralizing antibody virus antibody animal arthralgia C57BL mouse cell culture chikungunya Chikungunya virus human immunology knockout mouse macrophage metabolism mouse pathology physiology severity of illness index virology virus load virus replication Animals Antibodies, Neutralizing Antibodies, Viral Arthralgia Cells, Cultured Chikungunya Fever Chikungunya virus Humans Interferon-gamma Macrophages Mice Mice, Inbred C57BL Mice, Knockout Receptors, IgG Severity of Illness Index Viral Load Virus Replication
spellingShingle	Fc receptor Fc receptor IIa gamma interferon neutralizing antibody virus antibody animal arthralgia C57BL mouse cell culture chikungunya Chikungunya virus human immunology knockout mouse macrophage metabolism mouse pathology physiology severity of illness index virology virus load virus replication Animals Antibodies, Neutralizing Antibodies, Viral Arthralgia Cells, Cultured Chikungunya Fever Chikungunya virus Humans Interferon-gamma Macrophages Mice Mice, Inbred C57BL Mice, Knockout Receptors, IgG Severity of Illness Index Viral Load Virus Replication Lum, F.-M Couderc, T Chia, B.-S Ong, R.-Y Her, Z Chow, A Leo, Y.-S Kam, Y.-W Rénia, L Lecuit, M Ng, L.F.P Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity
description	10.1038/s41598-018-20305-4
author2	SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
author_facet	SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH Lum, F.-M Couderc, T Chia, B.-S Ong, R.-Y Her, Z Chow, A Leo, Y.-S Kam, Y.-W Rénia, L Lecuit, M Ng, L.F.P
format	Article
author	Lum, F.-M Couderc, T Chia, B.-S Ong, R.-Y Her, Z Chow, A Leo, Y.-S Kam, Y.-W Rénia, L Lecuit, M Ng, L.F.P
author_sort	Lum, F.-M
title	Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity
title_short	Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity
title_full	Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity
title_fullStr	Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity
title_full_unstemmed	Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity
title_sort	antibody-mediated enhancement aggravates chikungunya virus infection and disease severity
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/174342
_version_	1800914228063764480

Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity

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