Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy

• Main Authors: Hor, J.H, Soh, E.S.-Y, Tan, L.Y, Lim, V.J.W, Santosa, M.M, Winanto, Institute of Molecular and Cell Biology, 61 Biopolis Drive138673, Singapore, School of Biological Science, Nanyang Technological University637551, Singapore, Ho, B.X, Fan, Y, Soh, B.-S, Ng, S.-Y
• Other Authors: BIOLOGICAL SCIENCES
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: cyclin dependent kinase 4 inhibitor; cyclin dependent kinase 6 inhibitor; cyclin dependent kinase inhibitor; unclassified drug; Article; cell survival; controlled study; human; human cell; human tissue; induced pluripotent stem cell; motoneuron; nerve cell degeneration; nervous system development; neuroprotection; organoid; priority journal; spinal muscular atrophy
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174353
• Institution: National University of Singapore

10.1038/s41419-018-1081-0