Engineering a riboswitch-based genetic platform for the self-directed evolution of acid-Tolerant phenotypes

• Main Authors: Pham, H.L, Wong, A, Chua, N, Teo, W.S, Yew, W.S, Chang, M.W
• Other Authors: BIOCHEMISTRY
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: acid; carboxylic acid; bioremediation; cells and cell components; gene expression; genetic analysis; genetic engineering; metabolism; pH; phenotype; acid tolerance; Article; biosensor; biotechnology; controlled study; directed molecular evolution; genetic algorithm; host cell; metabolic engineering; nonhuman; nucleotide sequence; quorum sensing; recording; riboswitch; self directed evolution; wild type; Escherichia coli; genetics; genotype; mutation; procedures; Acids; Directed Molecular Evolution; Genetic Engineering; Genotype; Hydrogen-Ion Concentration; Mutation; Phenotype; Riboswitch
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174402
• Institution: National University of Singapore

10.1038/s41467-017-00511-w