Selinexor (KPT-330) has antitumor activity against anaplastic thyroid carcinoma in vitro and in vivo and enhances sensitivity to doxorubicin

10.1038/s41598-017-10325-x

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Bibliographic Details
Main Authors:	Garg, M, Kanojia, D, Mayakonda, A, Ganesan, T.S, Sadhanandhan, B, Suresh, S, Sneha, S, Nagare, R.P, Said, J.W, Doan, N.B, Ding, L.-W, Baloglu, E, Shacham, S, Kauffman, M, Koeffler, H.P
Other Authors:	CANCER SCIENCE INSTITUTE OF SINGAPORE
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	antineoplastic agent cell receptor doxorubicin exportin 1 protein hydrazine derivative karyopherin KPT-330 triazole derivative animal antagonists and inhibitors apoptosis biological model cancer transplantation cell cycle checkpoint disease model human thyroid carcinoma thyroid tumor treatment outcome tumor cell culture xenograft Animals Antineoplastic Agents Apoptosis Cell Cycle Checkpoints Disease Models, Animal Doxorubicin Heterografts Humans Hydrazines Karyopherins Models, Biological Neoplasm Transplantation Receptors, Cytoplasmic and Nuclear Thyroid Carcinoma, Anaplastic Thyroid Neoplasms Treatment Outcome Triazoles Tumor Cells, Cultured
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174403
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Institution:	National University of Singapore

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