Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme

Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme

10.1038/s41467-017-01392-9

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Bibliographic Details
Main Authors:	Newman J.P., Wang G.Y., Arima K., Guan S.P., Waters M.R., Cavenee W.K., Pan E., Aliwarga E., Chong S.T., Kok C.Y.L., Endaya B.B., Habib A.A., Horibe T., Ng W.H., Ho I.A.W., Hui K.M., Kordula T., Lam P.Y.P.
Other Authors:	MEDICINE
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	epidermal growth factor receptor epidermal growth factor receptor v III interleukin 13 interleukin 13 receptor alpha2 messenger RNA phosphatidylinositol 3 kinase protein variant STAT3 protein unclassified drug epidermal growth factor receptor VIII mitogen activated protein kinase mitogen activated protein kinase kinase kinase Raf protein Ras protein brain cancer cells and cell components enzyme enzyme activity inhibitor protein animal experiment animal model Article astrocyte cancer patient carcinogenesis cell invasion cell migration cell proliferation cell viability controlled study cytoplasm enzyme activation glioblastoma glioma cell line human human cell in vitro study in vivo study major clinical study MAPK signaling mouse nonhuman Pi3K/Akt signaling primary tumor protein expression protein phosphorylation signal transduction tumor xenograft U-251MG cell line animal brain tumor cancer transplantation gene knockdown genetics metabolism mortality mutation pathology survival rate tumor cell line tumor invasion Animals Brain Neoplasms Cell Line, Tumor Cell Proliferation Extracellular Signal-Regulated MAP Kinases Gene Knockdown Techniques Glioblastoma Humans In Vitro Techniques Interleukin-13 Receptor alpha2 Subunit MAP Kinase Kinase Kinases Mice Mutation Neoplasm Invasiveness Neoplasm Transplantation raf Kinases ras Proteins Receptor, Epidermal Growth Factor RNA, Messenger Survival Rate
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174482
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Institution:	National University of Singapore

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https://scholarbank.nus.edu.sg/handle/10635/174482