Leptin induces muscle wasting in a zebrafish kras-driven hepatocellular carcinoma (HCC) model

• Main Authors: Yang, Q., Yan, C., Wang, X., Gong, Z.
• Other Authors: BIOLOGY (NU)
• Format: Article
• Published: NLM (Medline) 2020
• Subjects: Kras protein, zebrafish; leptin; leptin receptor; protein p21; zebrafish protein; animal; carcinogenesis; disease model; fatty liver; feeding behavior; gene knockout; genetics; human; liver cell carcinoma; liver tumor; male; metabolism; muscle atrophy; mutation; pathology; signal transduction; upregulation; zebra fish; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Disease Models, Animal; Fatty Liver; Feeding Behavior; Gene Knockout Techniques; Humans; Leptin; Liver Neoplasms; Male; Muscular Atrophy; Mutation; Proto-Oncogene Proteins p21(ras); Receptors, Leptin; Signal Transduction; Up-Regulation; Zebrafish; Zebrafish Proteins
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174509
• Institution: National University of Singapore

10.1242/dmm.038240