Non-Invasive Multimodality Imaging Directly Shows TRPM4 Inhibition Ameliorates Stroke Reperfusion Injury

Non-Invasive Multimodality Imaging Directly Shows TRPM4 Inhibition Ameliorates Stroke Reperfusion Injury

10.1007/s12975-018-0621-3

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Bibliographic Details
Main Authors:	Chen B., Ng G., Gao Y., Low S.W., Sandanaraj E., Ramasamy B., Sekar S., Bhakoo K., Soong T.W., Nilius B., Tang C., Robins E.G., Goggi J., Liao P.
Other Authors:	DEAN'S OFFICE (MEDICINE)
Format:	Article
Published:	Springer 2020
Subjects:	claudin 1 claudin 2 Evans blue hemoglobin small interfering RNA transient receptor potential channel M4 von Willebrand factor enolase fluorodeoxyglucose f 18 messenger RNA transient receptor potential channel M TRPM4 protein, rat animal experiment animal model animal tissue Article blood brain barrier brain capillary endothelial cell brain edema brain infarction brain protection brain tissue cell survival cerebrovascular accident controlled study extravasation hemisphere human human cell in vitro study in vivo study infarct volume magnetic field male middle cerebral artery occlusion motor performance multimodal imaging nerve cell growth neuroimaging non invasive procedure nonhuman nuclear magnetic resonance imaging positron emission tomography priority journal protein expression rat reperfusion injury stroke patient animal antagonists and inhibitors cerebral artery disease complication disease model gene expression regulation genetics hemispheric dominance image processing metabolism microarray analysis pathology pathophysiology physiology procedures Wistar rat Animals Blood-Brain Barrier Brain Edema Disease Models, Animal Fluorodeoxyglucose F18 Functional Laterality Gene Expression Regulation Image Processing, Computer-Assisted Infarction, Middle Cerebral Artery Male Microarray Analysis Multimodal Imaging Phosphopyruvate Hydratase Rats Rats, Wistar Reperfusion Injury RNA, Messenger RNA, Small Interfering TRPM Cation Channels von Willebrand Factor
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174510
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Institution:	National University of Singapore

Description
Summary:	10.1007/s12975-018-0621-3