Localized delivery of pilocarpine to hypofunctional salivary glands through electrospun nanofiber mats: An ex vivo and in vivo study
10.3390/ijms20030541
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sg-nus-scholar.10635-1746592024-04-25T02:52:38Z Localized delivery of pilocarpine to hypofunctional salivary glands through electrospun nanofiber mats: An ex vivo and in vivo study Muthumariappan S. Ng W.C. Adine C. Ng K.K. Davoodi P. Wang C.-H. Ferreira J.N. BIOMEDICAL ENGINEERING CHEMICAL & BIOMOLECULAR ENGINEERING DENTISTRY NUS ENVIRONMENTAL RESEARCH INSTITUTE caspase 3 electrospun nanofiber Ki 67 antigen macrogol nanofiber pilocarpine polyglactin unclassified drug biomaterial nanofiber pilocarpine apoptosis Article biocompatibility biological activity cell proliferation cytotoxicity drug formulation drug release electrospinning encapsulation ex vivo study immunofluorescence in vivo study nonhuman protein degradation protein expression salivary gland scanning electron microscopy xerostomia animal C57BL mouse cell compartmentalization cell death chemistry drug delivery system drug effect female Institute for Cancer Research mouse intradermal drug administration metabolism pathophysiology saliva salivary gland treatment outcome ultrastructure Animals Biocompatible Materials Cell Compartmentation Cell Death Drug Delivery Systems Drug Liberation Female Injections, Intradermal Ki-67 Antigen Mice, Inbred C57BL Mice, Inbred ICR Nanofibers Pilocarpine Saliva Salivary Glands Treatment Outcome 10.3390/ijms20030541 International Journal of Molecular Sciences 20 3 541 2020-09-08T03:53:28Z 2020-09-08T03:53:28Z 2019 Article Muthumariappan S., Ng W.C., Adine C., Ng K.K., Davoodi P., Wang C.-H., Ferreira J.N. (2019). Localized delivery of pilocarpine to hypofunctional salivary glands through electrospun nanofiber mats: An ex vivo and in vivo study. International Journal of Molecular Sciences 20 (3) : 541. ScholarBank@NUS Repository. https://doi.org/10.3390/ijms20030541 1661-6596 https://scholarbank.nus.edu.sg/handle/10635/174659 Unpaywall 20200831 |
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caspase 3 electrospun nanofiber Ki 67 antigen macrogol nanofiber pilocarpine polyglactin unclassified drug biomaterial nanofiber pilocarpine apoptosis Article biocompatibility biological activity cell proliferation cytotoxicity drug formulation drug release electrospinning encapsulation ex vivo study immunofluorescence in vivo study nonhuman protein degradation protein expression salivary gland scanning electron microscopy xerostomia animal C57BL mouse cell compartmentalization cell death chemistry drug delivery system drug effect female Institute for Cancer Research mouse intradermal drug administration metabolism pathophysiology saliva salivary gland treatment outcome ultrastructure Animals Biocompatible Materials Cell Compartmentation Cell Death Drug Delivery Systems Drug Liberation Female Injections, Intradermal Ki-67 Antigen Mice, Inbred C57BL Mice, Inbred ICR Nanofibers Pilocarpine Saliva Salivary Glands Treatment Outcome |
| spellingShingle |
caspase 3 electrospun nanofiber Ki 67 antigen macrogol nanofiber pilocarpine polyglactin unclassified drug biomaterial nanofiber pilocarpine apoptosis Article biocompatibility biological activity cell proliferation cytotoxicity drug formulation drug release electrospinning encapsulation ex vivo study immunofluorescence in vivo study nonhuman protein degradation protein expression salivary gland scanning electron microscopy xerostomia animal C57BL mouse cell compartmentalization cell death chemistry drug delivery system drug effect female Institute for Cancer Research mouse intradermal drug administration metabolism pathophysiology saliva salivary gland treatment outcome ultrastructure Animals Biocompatible Materials Cell Compartmentation Cell Death Drug Delivery Systems Drug Liberation Female Injections, Intradermal Ki-67 Antigen Mice, Inbred C57BL Mice, Inbred ICR Nanofibers Pilocarpine Saliva Salivary Glands Treatment Outcome Muthumariappan S. Ng W.C. Adine C. Ng K.K. Davoodi P. Wang C.-H. Ferreira J.N. Localized delivery of pilocarpine to hypofunctional salivary glands through electrospun nanofiber mats: An ex vivo and in vivo study |
| description |
10.3390/ijms20030541 |
| author2 |
BIOMEDICAL ENGINEERING |
| author_facet |
BIOMEDICAL ENGINEERING Muthumariappan S. Ng W.C. Adine C. Ng K.K. Davoodi P. Wang C.-H. Ferreira J.N. |
| format |
Article |
| author |
Muthumariappan S. Ng W.C. Adine C. Ng K.K. Davoodi P. Wang C.-H. Ferreira J.N. |
| author_sort |
Muthumariappan S. |
| title |
Localized delivery of pilocarpine to hypofunctional salivary glands through electrospun nanofiber mats: An ex vivo and in vivo study |
| title_short |
Localized delivery of pilocarpine to hypofunctional salivary glands through electrospun nanofiber mats: An ex vivo and in vivo study |
| title_full |
Localized delivery of pilocarpine to hypofunctional salivary glands through electrospun nanofiber mats: An ex vivo and in vivo study |
| title_fullStr |
Localized delivery of pilocarpine to hypofunctional salivary glands through electrospun nanofiber mats: An ex vivo and in vivo study |
| title_full_unstemmed |
Localized delivery of pilocarpine to hypofunctional salivary glands through electrospun nanofiber mats: An ex vivo and in vivo study |
| title_sort |
localized delivery of pilocarpine to hypofunctional salivary glands through electrospun nanofiber mats: an ex vivo and in vivo study |
| publishDate |
2020 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/174659 |
| _version_ |
1800914266577960960 |