Gelsolin-Cu/ZnSOD interaction alters intracellular reactive oxygen species levels to promote cancer cell invasion

• Main Authors: Tochhawng, L, Deng, S, Pugalenthi, G, Kumar, A.P, Lim, K.H, Yang, H, Hooi, S.C, Goh, Y.C, Maciver, S.K, Pervaiz, S, Yap, C.T
• Other Authors: DEPT OF BIOCHEMISTRY
• Format: Article
• Published: Impact Journals LLC 2020
• Subjects: copper zinc superoxide dismutase; gelsolin; proteinase; reactive oxygen metabolite; urokinase; protein binding; Article; bioinformatics; cancer tissue; cell invasion; controlled study; enzyme activity; enzyme degradation; enzyme release; gelsolin gene; gene expression regulation; gene overexpression; HCT116 cell line; human; human cell; human tissue; in vitro study; microarray analysis; protein protein interaction; tumor invasion; upregulation; Caco-2 cell line; chemistry; colon tumor; gene expression profiling; genetics; HCT 116 cell line; HeLa cell line; Hep-G2 cell line; metabolism; molecular model; pathology; procedures; protein domain; RNA interference; tumor cell line; Caco-2 Cells; Cell Line, Tumor; Colonic Neoplasms; Gelsolin; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HCT116 Cells; HeLa Cells; Hep G2 Cells; Humans; Models, Molecular; Neoplasm Invasiveness; Protein Binding; Protein Domains; Reactive Oxygen Species; RNA Interference; Superoxide Dismutase-1; Urokinase-Type Plasminogen Activator
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174944
• Institution: National University of Singapore

10.18632/oncotarget.10451