GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers

10.1038/s41388-017-0038-6

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Main Authors:	Rasheed, S.A.K, Leong, H.S, Lakshmanan, M, Raju, A, Dadlani, D, Chong, F.-T, Shannon, N.B, Rajarethinam, R, Skanthakumar, T, Tan, E.Y, Hwang, J.S.G, Lim, K.H, Tan, D.S.-W, Ceppi, P, Wang, M, Tergaonkar, V, Casey, P.J, Iyer, N.G
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	antineoplastic agent cisplatin cytotoxic agent GNA13 protein GNA13 protein inhibitor guanine nucleotide binding protein protein inhibitor tumor marker unclassified drug guanine nucleotide binding protein alpha subunit animal cell animal experiment animal model animal tissue Article cancer growth cancer patient cancer prognosis cancer resistance cancer survival carcinoma cell controlled study head and neck squamous cell carcinoma human human cell in vitro study in vivo study metastasis mouse nonhuman phenotype priority journal protein expression protein function randomized controlled trial signal transduction solid malignant neoplasm tumor initiating phenotype upregulation animal cell proliferation cell transformation drug effect drug resistance drug therapy gene expression regulation genetics nonobese diabetic mouse pathology SCID mouse tumor cell culture Animals Antineoplastic Agents Biomarkers, Tumor Cell Proliferation Cell Transformation, Neoplastic Drug Resistance, Neoplasm Gene Expression Regulation, Neoplastic GTP-Binding Protein alpha Subunits Humans Mice Mice, Inbred NOD Mice, SCID Phenotype Signal Transduction Squamous Cell Carcinoma of Head and Neck Tumor Cells, Cultured
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/175123
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1751232023-08-29T21:58:19Z GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers Rasheed, S.A.K Leong, H.S Lakshmanan, M Raju, A Dadlani, D Chong, F.-T Shannon, N.B Rajarethinam, R Skanthakumar, T Tan, E.Y Hwang, J.S.G Lim, K.H Tan, D.S.-W Ceppi, P Wang, M Tergaonkar, V Casey, P.J Iyer, N.G DUKE-NUS MEDICAL SCHOOL antineoplastic agent cisplatin cytotoxic agent GNA13 protein GNA13 protein inhibitor guanine nucleotide binding protein protein inhibitor tumor marker unclassified drug antineoplastic agent guanine nucleotide binding protein alpha subunit tumor marker animal cell animal experiment animal model animal tissue Article cancer growth cancer patient cancer prognosis cancer resistance cancer survival carcinoma cell controlled study head and neck squamous cell carcinoma human human cell in vitro study in vivo study metastasis mouse nonhuman phenotype priority journal protein expression protein function randomized controlled trial signal transduction solid malignant neoplasm tumor initiating phenotype upregulation animal cell proliferation cell transformation drug effect drug resistance drug therapy gene expression regulation genetics nonobese diabetic mouse pathology phenotype SCID mouse tumor cell culture Animals Antineoplastic Agents Biomarkers, Tumor Cell Proliferation Cell Transformation, Neoplastic Drug Resistance, Neoplasm Gene Expression Regulation, Neoplastic GTP-Binding Protein alpha Subunits Humans Mice Mice, Inbred NOD Mice, SCID Phenotype Signal Transduction Squamous Cell Carcinoma of Head and Neck Tumor Cells, Cultured 10.1038/s41388-017-0038-6 Oncogene 37 10 1340-1353 2020-09-09T04:10:54Z 2020-09-09T04:10:54Z 2018 Article Rasheed, S.A.K, Leong, H.S, Lakshmanan, M, Raju, A, Dadlani, D, Chong, F.-T, Shannon, N.B, Rajarethinam, R, Skanthakumar, T, Tan, E.Y, Hwang, J.S.G, Lim, K.H, Tan, D.S.-W, Ceppi, P, Wang, M, Tergaonkar, V, Casey, P.J, Iyer, N.G (2018). GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers. Oncogene 37 (10) : 1340-1353. ScholarBank@NUS Repository. https://doi.org/10.1038/s41388-017-0038-6 0950-9232 https://scholarbank.nus.edu.sg/handle/10635/175123 Nature Publishing Group Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	antineoplastic agent cisplatin cytotoxic agent GNA13 protein GNA13 protein inhibitor guanine nucleotide binding protein protein inhibitor tumor marker unclassified drug antineoplastic agent guanine nucleotide binding protein alpha subunit tumor marker animal cell animal experiment animal model animal tissue Article cancer growth cancer patient cancer prognosis cancer resistance cancer survival carcinoma cell controlled study head and neck squamous cell carcinoma human human cell in vitro study in vivo study metastasis mouse nonhuman phenotype priority journal protein expression protein function randomized controlled trial signal transduction solid malignant neoplasm tumor initiating phenotype upregulation animal cell proliferation cell transformation drug effect drug resistance drug therapy gene expression regulation genetics nonobese diabetic mouse pathology phenotype SCID mouse tumor cell culture Animals Antineoplastic Agents Biomarkers, Tumor Cell Proliferation Cell Transformation, Neoplastic Drug Resistance, Neoplasm Gene Expression Regulation, Neoplastic GTP-Binding Protein alpha Subunits Humans Mice Mice, Inbred NOD Mice, SCID Phenotype Signal Transduction Squamous Cell Carcinoma of Head and Neck Tumor Cells, Cultured
spellingShingle	antineoplastic agent cisplatin cytotoxic agent GNA13 protein GNA13 protein inhibitor guanine nucleotide binding protein protein inhibitor tumor marker unclassified drug antineoplastic agent guanine nucleotide binding protein alpha subunit tumor marker animal cell animal experiment animal model animal tissue Article cancer growth cancer patient cancer prognosis cancer resistance cancer survival carcinoma cell controlled study head and neck squamous cell carcinoma human human cell in vitro study in vivo study metastasis mouse nonhuman phenotype priority journal protein expression protein function randomized controlled trial signal transduction solid malignant neoplasm tumor initiating phenotype upregulation animal cell proliferation cell transformation drug effect drug resistance drug therapy gene expression regulation genetics nonobese diabetic mouse pathology phenotype SCID mouse tumor cell culture Animals Antineoplastic Agents Biomarkers, Tumor Cell Proliferation Cell Transformation, Neoplastic Drug Resistance, Neoplasm Gene Expression Regulation, Neoplastic GTP-Binding Protein alpha Subunits Humans Mice Mice, Inbred NOD Mice, SCID Phenotype Signal Transduction Squamous Cell Carcinoma of Head and Neck Tumor Cells, Cultured Rasheed, S.A.K Leong, H.S Lakshmanan, M Raju, A Dadlani, D Chong, F.-T Shannon, N.B Rajarethinam, R Skanthakumar, T Tan, E.Y Hwang, J.S.G Lim, K.H Tan, D.S.-W Ceppi, P Wang, M Tergaonkar, V Casey, P.J Iyer, N.G GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers
description	10.1038/s41388-017-0038-6
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Rasheed, S.A.K Leong, H.S Lakshmanan, M Raju, A Dadlani, D Chong, F.-T Shannon, N.B Rajarethinam, R Skanthakumar, T Tan, E.Y Hwang, J.S.G Lim, K.H Tan, D.S.-W Ceppi, P Wang, M Tergaonkar, V Casey, P.J Iyer, N.G
format	Article
author	Rasheed, S.A.K Leong, H.S Lakshmanan, M Raju, A Dadlani, D Chong, F.-T Shannon, N.B Rajarethinam, R Skanthakumar, T Tan, E.Y Hwang, J.S.G Lim, K.H Tan, D.S.-W Ceppi, P Wang, M Tergaonkar, V Casey, P.J Iyer, N.G
author_sort	Rasheed, S.A.K
title	GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers
title_short	GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers
title_full	GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers
title_fullStr	GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers
title_full_unstemmed	GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers
title_sort	gna13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/175123
_version_	1778169857056964608

GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers

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