Andrographolide suppresses MV4-11 cell proliferation through the inhibition of FLT3 signaling, fatty acid synthesis and cellular iron uptake

• Main Authors: Chen, X, Zhang, J, Yuan, L, Lay, Y, Wong, Y.K, Lim, T.K, Ong, C.S, Lin, Q, Wang, J, Hua, Z
• Other Authors: BIOLOGICAL SCIENCES
• Format: Article
• Published: MDPI AG 2020
• Subjects: andrographolide; antineoplastic agent; CD135 antigen; diterpene; fatty acid; FLT3 protein, human; iron; biosynthesis; cell proliferation; cell survival; drug effect; drug screening; human; metabolism; protein synthesis; signal transduction; tumor cell line; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diterpenes; Drug Screening Assays, Antitumor; Fatty Acids; fms-Like Tyrosine Kinase 3; Humans; Iron; Protein Biosynthesis; Signal Transduction
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175150
• Institution: National University of Singapore

10.3390/molecules22091444