Artesunate activates the intrinsic apoptosis of HCT116 cells through the suppression of fatty acid synthesis and the NF-?B pathway

10.3390/molecules22081272

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Main Authors: Chen, X, Wong, Y.K, Lim, T.K, Lim, W.H, Lin, Q, Wang, J, Hua, Z
Other Authors: BIOLOGICAL SCIENCES
Format: Article
Published: MDPI AG 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/175156
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spelling sg-nus-scholar.10635-1751562024-04-04T01:11:30Z Artesunate activates the intrinsic apoptosis of HCT116 cells through the suppression of fatty acid synthesis and the NF-?B pathway Chen, X Wong, Y.K Lim, T.K Lim, W.H Lin, Q Wang, J Hua, Z BIOLOGICAL SCIENCES BIOLOGY (NU) PHYSIOLOGY artemisinin derivative artesunate fatty acid immunoglobulin enhancer binding protein reactive oxygen metabolite apoptosis biological model biosynthesis cell proliferation cell survival dose response drug effects HCT 116 cell line human metabolism mitochondrion procedures proteomics signal transduction Apoptosis Artemisinins Biosynthetic Pathways Cell Proliferation Cell Survival Dose-Response Relationship, Drug Fatty Acids HCT116 Cells Humans Mitochondria Models, Biological NF-kappa B Proteomics Reactive Oxygen Species Signal Transduction 10.3390/molecules22081272 Molecules 22 8 1272 2020-09-09T04:18:13Z 2020-09-09T04:18:13Z 2017 Article Chen, X, Wong, Y.K, Lim, T.K, Lim, W.H, Lin, Q, Wang, J, Hua, Z (2017). Artesunate activates the intrinsic apoptosis of HCT116 cells through the suppression of fatty acid synthesis and the NF-?B pathway. Molecules 22 (8) : 1272. ScholarBank@NUS Repository. https://doi.org/10.3390/molecules22081272 1420-3049 https://scholarbank.nus.edu.sg/handle/10635/175156 MDPI AG Unpaywall 20200831
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic artemisinin derivative
artesunate
fatty acid
immunoglobulin enhancer binding protein
reactive oxygen metabolite
apoptosis
biological model
biosynthesis
cell proliferation
cell survival
dose response
drug effects
HCT 116 cell line
human
metabolism
mitochondrion
procedures
proteomics
signal transduction
Apoptosis
Artemisinins
Biosynthetic Pathways
Cell Proliferation
Cell Survival
Dose-Response Relationship, Drug
Fatty Acids
HCT116 Cells
Humans
Mitochondria
Models, Biological
NF-kappa B
Proteomics
Reactive Oxygen Species
Signal Transduction
spellingShingle artemisinin derivative
artesunate
fatty acid
immunoglobulin enhancer binding protein
reactive oxygen metabolite
apoptosis
biological model
biosynthesis
cell proliferation
cell survival
dose response
drug effects
HCT 116 cell line
human
metabolism
mitochondrion
procedures
proteomics
signal transduction
Apoptosis
Artemisinins
Biosynthetic Pathways
Cell Proliferation
Cell Survival
Dose-Response Relationship, Drug
Fatty Acids
HCT116 Cells
Humans
Mitochondria
Models, Biological
NF-kappa B
Proteomics
Reactive Oxygen Species
Signal Transduction
Chen, X
Wong, Y.K
Lim, T.K
Lim, W.H
Lin, Q
Wang, J
Hua, Z
Artesunate activates the intrinsic apoptosis of HCT116 cells through the suppression of fatty acid synthesis and the NF-?B pathway
description 10.3390/molecules22081272
author2 BIOLOGICAL SCIENCES
author_facet BIOLOGICAL SCIENCES
Chen, X
Wong, Y.K
Lim, T.K
Lim, W.H
Lin, Q
Wang, J
Hua, Z
format Article
author Chen, X
Wong, Y.K
Lim, T.K
Lim, W.H
Lin, Q
Wang, J
Hua, Z
author_sort Chen, X
title Artesunate activates the intrinsic apoptosis of HCT116 cells through the suppression of fatty acid synthesis and the NF-?B pathway
title_short Artesunate activates the intrinsic apoptosis of HCT116 cells through the suppression of fatty acid synthesis and the NF-?B pathway
title_full Artesunate activates the intrinsic apoptosis of HCT116 cells through the suppression of fatty acid synthesis and the NF-?B pathway
title_fullStr Artesunate activates the intrinsic apoptosis of HCT116 cells through the suppression of fatty acid synthesis and the NF-?B pathway
title_full_unstemmed Artesunate activates the intrinsic apoptosis of HCT116 cells through the suppression of fatty acid synthesis and the NF-?B pathway
title_sort artesunate activates the intrinsic apoptosis of hct116 cells through the suppression of fatty acid synthesis and the nf-?b pathway
publisher MDPI AG
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/175156
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