Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib

10.1038/s41598-017-01491-z

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Main Authors: Kannan, S, Pradhan, M.R, Tiwari, G, Tan, W.-C, Chowbay, B, Tan, E.H, Tan, D.S.-W, Verma, C
Other Authors: DUKE-NUS MEDICAL SCHOOL
Format: Article
Published: 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/175187
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spelling sg-nus-scholar.10635-1751872023-09-13T21:11:01Z Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib Kannan, S Pradhan, M.R Tiwari, G Tan, W.-C Chowbay, B Tan, E.H Tan, D.S.-W Verma, C DUKE-NUS MEDICAL SCHOOL BIOLOGY (NU) afatinib epidermal growth factor receptor ligand water antagonists and inhibitors binding site chemistry enzyme activation genetics human molecular dynamics mutation Afatinib Binding Sites Enzyme Activation ErbB Receptors Humans Ligands Molecular Dynamics Simulation Mutation Water 10.1038/s41598-017-01491-z Scientific Reports 7 1 1540 2020-09-09T04:56:37Z 2020-09-09T04:56:37Z 2017 Article Kannan, S, Pradhan, M.R, Tiwari, G, Tan, W.-C, Chowbay, B, Tan, E.H, Tan, D.S.-W, Verma, C (2017). Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib. Scientific Reports 7 (1) : 1540. ScholarBank@NUS Repository. https://doi.org/10.1038/s41598-017-01491-z 20452322 https://scholarbank.nus.edu.sg/handle/10635/175187 Unpaywall 20200831
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic afatinib
epidermal growth factor receptor
ligand
water
antagonists and inhibitors
binding site
chemistry
enzyme activation
genetics
human
molecular dynamics
mutation
Afatinib
Binding Sites
Enzyme Activation
ErbB Receptors
Humans
Ligands
Molecular Dynamics Simulation
Mutation
Water
spellingShingle afatinib
epidermal growth factor receptor
ligand
water
antagonists and inhibitors
binding site
chemistry
enzyme activation
genetics
human
molecular dynamics
mutation
Afatinib
Binding Sites
Enzyme Activation
ErbB Receptors
Humans
Ligands
Molecular Dynamics Simulation
Mutation
Water
Kannan, S
Pradhan, M.R
Tiwari, G
Tan, W.-C
Chowbay, B
Tan, E.H
Tan, D.S.-W
Verma, C
Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib
description 10.1038/s41598-017-01491-z
author2 DUKE-NUS MEDICAL SCHOOL
author_facet DUKE-NUS MEDICAL SCHOOL
Kannan, S
Pradhan, M.R
Tiwari, G
Tan, W.-C
Chowbay, B
Tan, E.H
Tan, D.S.-W
Verma, C
format Article
author Kannan, S
Pradhan, M.R
Tiwari, G
Tan, W.-C
Chowbay, B
Tan, E.H
Tan, D.S.-W
Verma, C
author_sort Kannan, S
title Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib
title_short Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib
title_full Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib
title_fullStr Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib
title_full_unstemmed Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib
title_sort hydration effects on the efficacy of the epidermal growth factor receptor kinase inhibitor afatinib
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/175187
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