Small molecule targeting malaria Merozoite surface protein-1 (MSP-1) prevents host invasion of divergent Plasmodial species

Small molecule targeting malaria Merozoite surface protein-1 (MSP-1) prevents host invasion of divergent Plasmodial species

10.1093/infdis/jiu296

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Bibliographic Details
Main Authors:	Chandramohanadas R., Russell B., Liew K., Yau Y.H., Chong A., Liu M., Gunalan K., Raman R., Renia L., Nosten F., Shochat S.G., Dao M., Sasisekharan R., Suresh S., Preiser P.
Other Authors:	MICROBIOLOGY AND IMMUNOLOGY
Format:	Article
Published:	Oxford University Press 2020
Subjects:	2 butyl 5 chloro 3 (4 nitro benzyl) 3h imidazole 4 carbaldehyde ligand merozoite surface protein 1 unclassified drug antimalarial agent Article binding affinity carboxy terminal sequence computer model controlled study in vitro study merozoite molecular docking nonhuman parasite phenomena and functions Plasmodium falciparum Plasmodium vivax protein analysis protein binding protein localization protein protein interaction sequence alignment species invasion surface plasmon resonance antagonists and inhibitors drug effects endocytosis human isolation and purification Antimalarials Endocytosis Humans Merozoite Surface Protein 1
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/175315
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Institution:	National University of Singapore

Description
Summary:	10.1093/infdis/jiu296