Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions

• Main Authors: Suram, A, Kaplunov, J, Patel, P.L, Ruan, H, Cerutti, A, Boccardi, V, Fumagalli, M, Di Micco, R, Mirani, N, Gurung, R.L, Hande, M.P, D'Adda Di Fagagna, F, Herbig, U
• Other Authors: PHYSIOLOGY
• Format: Article
• Published: 2020
• Subjects: beta galactosidase; Ki 67 antigen; protein p16; telomerase; animal cell; article; cancer growth; cell aging; cell proliferation; chromosome structure; controlled study; DNA replication; enzyme activity; gene replication; human; human cell; human tissue; nonhuman; oncogene; priority journal; telomere; telomere dysfunction induced senescence; Cell Aging; Cell Line; Cell Transformation, Neoplastic; DNA Replication; Humans; Oncogenes; Protein Synthesis Inhibitors; Puromycin; Signal Transduction; Telomere
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175333
• Institution: National University of Singapore

10.1038/emboj.2012.132