Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions

10.1038/emboj.2012.132

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Main Authors:	Suram, A, Kaplunov, J, Patel, P.L, Ruan, H, Cerutti, A, Boccardi, V, Fumagalli, M, Di Micco, R, Mirani, N, Gurung, R.L, Hande, M.P, D'Adda Di Fagagna, F, Herbig, U
Other Authors:	PHYSIOLOGY
Format:	Article
Published:	2020
Subjects:	beta galactosidase Ki 67 antigen protein p16 telomerase animal cell article cancer growth cell aging cell proliferation chromosome structure controlled study DNA replication enzyme activity gene replication human human cell human tissue nonhuman oncogene priority journal telomere telomere dysfunction induced senescence Cell Aging Cell Line Cell Transformation, Neoplastic DNA Replication Humans Oncogenes Protein Synthesis Inhibitors Puromycin Signal Transduction Telomere
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/175333
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-175333
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spelling	sg-nus-scholar.10635-1753332024-04-04T01:10:08Z Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions Suram, A Kaplunov, J Patel, P.L Ruan, H Cerutti, A Boccardi, V Fumagalli, M Di Micco, R Mirani, N Gurung, R.L Hande, M.P D'Adda Di Fagagna, F Herbig, U PHYSIOLOGY beta galactosidase Ki 67 antigen protein p16 telomerase animal cell article cancer growth cell aging cell proliferation chromosome structure controlled study DNA replication enzyme activity gene replication human human cell human tissue nonhuman oncogene priority journal telomere telomere dysfunction induced senescence Cell Aging Cell Line Cell Transformation, Neoplastic DNA Replication Humans Oncogenes Protein Synthesis Inhibitors Puromycin Signal Transduction Telomere 10.1038/emboj.2012.132 EMBO Journal 31 13 2839-2851 2020-09-09T09:45:25Z 2020-09-09T09:45:25Z 2012 Article Suram, A, Kaplunov, J, Patel, P.L, Ruan, H, Cerutti, A, Boccardi, V, Fumagalli, M, Di Micco, R, Mirani, N, Gurung, R.L, Hande, M.P, D'Adda Di Fagagna, F, Herbig, U (2012). Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions. EMBO Journal 31 (13) : 2839-2851. ScholarBank@NUS Repository. https://doi.org/10.1038/emboj.2012.132 0261-4189 https://scholarbank.nus.edu.sg/handle/10635/175333 Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	beta galactosidase Ki 67 antigen protein p16 telomerase animal cell article cancer growth cell aging cell proliferation chromosome structure controlled study DNA replication enzyme activity gene replication human human cell human tissue nonhuman oncogene priority journal telomere telomere dysfunction induced senescence Cell Aging Cell Line Cell Transformation, Neoplastic DNA Replication Humans Oncogenes Protein Synthesis Inhibitors Puromycin Signal Transduction Telomere
spellingShingle	beta galactosidase Ki 67 antigen protein p16 telomerase animal cell article cancer growth cell aging cell proliferation chromosome structure controlled study DNA replication enzyme activity gene replication human human cell human tissue nonhuman oncogene priority journal telomere telomere dysfunction induced senescence Cell Aging Cell Line Cell Transformation, Neoplastic DNA Replication Humans Oncogenes Protein Synthesis Inhibitors Puromycin Signal Transduction Telomere Suram, A Kaplunov, J Patel, P.L Ruan, H Cerutti, A Boccardi, V Fumagalli, M Di Micco, R Mirani, N Gurung, R.L Hande, M.P D'Adda Di Fagagna, F Herbig, U Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions
description	10.1038/emboj.2012.132
author2	PHYSIOLOGY
author_facet	PHYSIOLOGY Suram, A Kaplunov, J Patel, P.L Ruan, H Cerutti, A Boccardi, V Fumagalli, M Di Micco, R Mirani, N Gurung, R.L Hande, M.P D'Adda Di Fagagna, F Herbig, U
format	Article
author	Suram, A Kaplunov, J Patel, P.L Ruan, H Cerutti, A Boccardi, V Fumagalli, M Di Micco, R Mirani, N Gurung, R.L Hande, M.P D'Adda Di Fagagna, F Herbig, U
author_sort	Suram, A
title	Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions
title_short	Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions
title_full	Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions
title_fullStr	Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions
title_full_unstemmed	Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions
title_sort	oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/175333
_version_	1795374375361314816

Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions

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