Intracellular hyper-acidification potentiated by hydrogen sulfide mediates invasive and therapy resistant cancer cell death

10.3389/fphar.2017.00763

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Main Authors:	Lee Z.-W., Teo X.-Y., Song Z.J., Nin D.S., Novera W., Choo B.A., Dymock B.W., Moore P.K., Huang R.Y.-J., Deng L.-W.
Other Authors:	CANCER SCIENCE INSTITUTE OF SINGAPORE
Format:	Article
Published:	2020
Subjects:	antineoplastic agent gyy 4137 hydrogen sulfide lactic acid metformin simvastatin unclassified drug A-549 cell line acidification Article bioenergy cancer cell cancer resistance cell death cell pH cell viability concentration response controlled study drug activity drug cytotoxicity drug potency drug potentiation drug response DU145 cell line glycolytic activity HeLa cell line intracellular hyperacidification LNCaP cell line MCF-7 cell line MDA-MB-231 cell line NCI-H1299 cell line procedures concerning cells radiosensitivity SiHa cell line
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/175420
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-175420
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spelling	sg-nus-scholar.10635-1754202024-04-24T05:52:52Z Intracellular hyper-acidification potentiated by hydrogen sulfide mediates invasive and therapy resistant cancer cell death Lee Z.-W. Teo X.-Y. Song Z.J. Nin D.S. Novera W. Choo B.A. Dymock B.W. Moore P.K. Huang R.Y.-J. Deng L.-W. CANCER SCIENCE INSTITUTE OF SINGAPORE BIOCHEMISTRY MEDICINE PHARMACOLOGY PHARMACY LIFE SCIENCES INSTITUTE antineoplastic agent gyy 4137 hydrogen sulfide lactic acid metformin simvastatin unclassified drug A-549 cell line acidification Article bioenergy cancer cell cancer resistance cell death cell pH cell viability concentration response controlled study drug activity drug cytotoxicity drug potency drug potentiation drug response DU145 cell line glycolytic activity HeLa cell line intracellular hyperacidification LNCaP cell line MCF-7 cell line MDA-MB-231 cell line NCI-H1299 cell line procedures concerning cells radiosensitivity SiHa cell line 10.3389/fphar.2017.00763 Frontiers in Pharmacology 8 OCT 763 2020-09-09T10:34:23Z 2020-09-09T10:34:23Z 2017 Article Lee Z.-W., Teo X.-Y., Song Z.J., Nin D.S., Novera W., Choo B.A., Dymock B.W., Moore P.K., Huang R.Y.-J., Deng L.-W. (2017). Intracellular hyper-acidification potentiated by hydrogen sulfide mediates invasive and therapy resistant cancer cell death. Frontiers in Pharmacology 8 (OCT) : 763. ScholarBank@NUS Repository. https://doi.org/10.3389/fphar.2017.00763 1663-9812 https://scholarbank.nus.edu.sg/handle/10635/175420 Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	antineoplastic agent gyy 4137 hydrogen sulfide lactic acid metformin simvastatin unclassified drug A-549 cell line acidification Article bioenergy cancer cell cancer resistance cell death cell pH cell viability concentration response controlled study drug activity drug cytotoxicity drug potency drug potentiation drug response DU145 cell line glycolytic activity HeLa cell line intracellular hyperacidification LNCaP cell line MCF-7 cell line MDA-MB-231 cell line NCI-H1299 cell line procedures concerning cells radiosensitivity SiHa cell line
spellingShingle	antineoplastic agent gyy 4137 hydrogen sulfide lactic acid metformin simvastatin unclassified drug A-549 cell line acidification Article bioenergy cancer cell cancer resistance cell death cell pH cell viability concentration response controlled study drug activity drug cytotoxicity drug potency drug potentiation drug response DU145 cell line glycolytic activity HeLa cell line intracellular hyperacidification LNCaP cell line MCF-7 cell line MDA-MB-231 cell line NCI-H1299 cell line procedures concerning cells radiosensitivity SiHa cell line Lee Z.-W. Teo X.-Y. Song Z.J. Nin D.S. Novera W. Choo B.A. Dymock B.W. Moore P.K. Huang R.Y.-J. Deng L.-W. Intracellular hyper-acidification potentiated by hydrogen sulfide mediates invasive and therapy resistant cancer cell death
description	10.3389/fphar.2017.00763
author2	CANCER SCIENCE INSTITUTE OF SINGAPORE
author_facet	CANCER SCIENCE INSTITUTE OF SINGAPORE Lee Z.-W. Teo X.-Y. Song Z.J. Nin D.S. Novera W. Choo B.A. Dymock B.W. Moore P.K. Huang R.Y.-J. Deng L.-W.
format	Article
author	Lee Z.-W. Teo X.-Y. Song Z.J. Nin D.S. Novera W. Choo B.A. Dymock B.W. Moore P.K. Huang R.Y.-J. Deng L.-W.
author_sort	Lee Z.-W.
title	Intracellular hyper-acidification potentiated by hydrogen sulfide mediates invasive and therapy resistant cancer cell death
title_short	Intracellular hyper-acidification potentiated by hydrogen sulfide mediates invasive and therapy resistant cancer cell death
title_full	Intracellular hyper-acidification potentiated by hydrogen sulfide mediates invasive and therapy resistant cancer cell death
title_fullStr	Intracellular hyper-acidification potentiated by hydrogen sulfide mediates invasive and therapy resistant cancer cell death
title_full_unstemmed	Intracellular hyper-acidification potentiated by hydrogen sulfide mediates invasive and therapy resistant cancer cell death
title_sort	intracellular hyper-acidification potentiated by hydrogen sulfide mediates invasive and therapy resistant cancer cell death
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/175420
_version_	1800914365146202112

Intracellular hyper-acidification potentiated by hydrogen sulfide mediates invasive and therapy resistant cancer cell death

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