Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck

10.1038/srep19552

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Main Authors: Huang, K.K, Jang, K.W, Kim, S, Kim, H.S, Kim, S.-M, Kwon, H.J, Kim, H.R, Yun, H.J, Ahn, M.J, Park, K.U, Ramnarayanan, K, McPherson, J.R, Zhang, S, Rhee, J.-K, Vettore, A.L, Das, K, Ishimoto, T, Kim, J.H, Koh, Y.W, Kim, S.H, Choi, E.C, Teh, B.T, Rozen, S.G, Kim, T.-M, Tan, P, Cho, B.C
Other Authors: DUKE-NUS MEDICAL SCHOOL
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Published: Nature Publishing Group 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/175438
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spelling sg-nus-scholar.10635-1754382024-04-04T01:10:35Z Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck Huang, K.K Jang, K.W Kim, S Kim, H.S Kim, S.-M Kwon, H.J Kim, H.R Yun, H.J Ahn, M.J Park, K.U Ramnarayanan, K McPherson, J.R Zhang, S Rhee, J.-K Vettore, A.L Das, K Ishimoto, T Kim, J.H Koh, Y.W Kim, S.H Choi, E.C Teh, B.T Rozen, S.G Kim, T.-M Tan, P Cho, B.C DUKE-NUS MEDICAL SCHOOL PHYSIOLOGY cisplatin dacomitinib DNA binding protein DNA directed DNA polymerase quinazolinone derivative REV3L protein, human small interfering RNA Carcinoma, Squamous Cell dna mutational analysis drug resistance exome gene silencing genetics Head and Neck Neoplasms high throughput sequencing human mutation recombination repair RNA interference tumor cell line Carcinoma, Squamous Cell Cell Line, Tumor Cisplatin DNA Mutational Analysis DNA-Binding Proteins DNA-Directed DNA Polymerase Drug Resistance, Neoplasm Exome Gene Silencing Head and Neck Neoplasms High-Throughput Nucleotide Sequencing Humans Mutation Quinazolinones Recombinational DNA Repair RNA Interference RNA, Small Interfering 10.1038/srep19552 Scientific Reports 6 19552 2020-09-10T01:40:55Z 2020-09-10T01:40:55Z 2016 Article Huang, K.K, Jang, K.W, Kim, S, Kim, H.S, Kim, S.-M, Kwon, H.J, Kim, H.R, Yun, H.J, Ahn, M.J, Park, K.U, Ramnarayanan, K, McPherson, J.R, Zhang, S, Rhee, J.-K, Vettore, A.L, Das, K, Ishimoto, T, Kim, J.H, Koh, Y.W, Kim, S.H, Choi, E.C, Teh, B.T, Rozen, S.G, Kim, T.-M, Tan, P, Cho, B.C (2016). Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck. Scientific Reports 6 : 19552. ScholarBank@NUS Repository. https://doi.org/10.1038/srep19552 20452322 https://scholarbank.nus.edu.sg/handle/10635/175438 Nature Publishing Group Unpaywall 20200831
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic cisplatin
dacomitinib
DNA binding protein
DNA directed DNA polymerase
quinazolinone derivative
REV3L protein, human
small interfering RNA
Carcinoma, Squamous Cell
dna mutational analysis
drug resistance
exome
gene silencing
genetics
Head and Neck Neoplasms
high throughput sequencing
human
mutation
recombination repair
RNA interference
tumor cell line
Carcinoma, Squamous Cell
Cell Line, Tumor
Cisplatin
DNA Mutational Analysis
DNA-Binding Proteins
DNA-Directed DNA Polymerase
Drug Resistance, Neoplasm
Exome
Gene Silencing
Head and Neck Neoplasms
High-Throughput Nucleotide Sequencing
Humans
Mutation
Quinazolinones
Recombinational DNA Repair
RNA Interference
RNA, Small Interfering
spellingShingle cisplatin
dacomitinib
DNA binding protein
DNA directed DNA polymerase
quinazolinone derivative
REV3L protein, human
small interfering RNA
Carcinoma, Squamous Cell
dna mutational analysis
drug resistance
exome
gene silencing
genetics
Head and Neck Neoplasms
high throughput sequencing
human
mutation
recombination repair
RNA interference
tumor cell line
Carcinoma, Squamous Cell
Cell Line, Tumor
Cisplatin
DNA Mutational Analysis
DNA-Binding Proteins
DNA-Directed DNA Polymerase
Drug Resistance, Neoplasm
Exome
Gene Silencing
Head and Neck Neoplasms
High-Throughput Nucleotide Sequencing
Humans
Mutation
Quinazolinones
Recombinational DNA Repair
RNA Interference
RNA, Small Interfering
Huang, K.K
Jang, K.W
Kim, S
Kim, H.S
Kim, S.-M
Kwon, H.J
Kim, H.R
Yun, H.J
Ahn, M.J
Park, K.U
Ramnarayanan, K
McPherson, J.R
Zhang, S
Rhee, J.-K
Vettore, A.L
Das, K
Ishimoto, T
Kim, J.H
Koh, Y.W
Kim, S.H
Choi, E.C
Teh, B.T
Rozen, S.G
Kim, T.-M
Tan, P
Cho, B.C
Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck
description 10.1038/srep19552
author2 DUKE-NUS MEDICAL SCHOOL
author_facet DUKE-NUS MEDICAL SCHOOL
Huang, K.K
Jang, K.W
Kim, S
Kim, H.S
Kim, S.-M
Kwon, H.J
Kim, H.R
Yun, H.J
Ahn, M.J
Park, K.U
Ramnarayanan, K
McPherson, J.R
Zhang, S
Rhee, J.-K
Vettore, A.L
Das, K
Ishimoto, T
Kim, J.H
Koh, Y.W
Kim, S.H
Choi, E.C
Teh, B.T
Rozen, S.G
Kim, T.-M
Tan, P
Cho, B.C
format Article
author Huang, K.K
Jang, K.W
Kim, S
Kim, H.S
Kim, S.-M
Kwon, H.J
Kim, H.R
Yun, H.J
Ahn, M.J
Park, K.U
Ramnarayanan, K
McPherson, J.R
Zhang, S
Rhee, J.-K
Vettore, A.L
Das, K
Ishimoto, T
Kim, J.H
Koh, Y.W
Kim, S.H
Choi, E.C
Teh, B.T
Rozen, S.G
Kim, T.-M
Tan, P
Cho, B.C
author_sort Huang, K.K
title Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck
title_short Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck
title_full Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck
title_fullStr Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck
title_full_unstemmed Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck
title_sort exome sequencing reveals recurrent rev3l mutations in cisplatin-resistant squamous cell carcinoma of head and neck
publisher Nature Publishing Group
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/175438
_version_ 1795374379559813120