Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck

• Main Authors: Huang, K.K, Jang, K.W, Kim, S, Kim, H.S, Kim, S.-M, Kwon, H.J, Kim, H.R, Yun, H.J, Ahn, M.J, Park, K.U, Ramnarayanan, K, McPherson, J.R, Zhang, S, Rhee, J.-K, Vettore, A.L, Das, K, Ishimoto, T, Kim, J.H, Koh, Y.W, Kim, S.H, Choi, E.C, Teh, B.T, Rozen, S.G, Kim, T.-M, Tan, P, Cho, B.C
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: cisplatin; dacomitinib; DNA binding protein; DNA directed DNA polymerase; quinazolinone derivative; REV3L protein, human; small interfering RNA; Carcinoma, Squamous Cell; dna mutational analysis; drug resistance; exome; gene silencing; genetics; Head and Neck Neoplasms; high throughput sequencing; human; mutation; recombination repair; RNA interference; tumor cell line; Cell Line, Tumor; Cisplatin; DNA Mutational Analysis; DNA-Binding Proteins; DNA-Directed DNA Polymerase; Drug Resistance, Neoplasm; Exome; Gene Silencing; High-Throughput Nucleotide Sequencing; Humans; Mutation; Quinazolinones; Recombinational DNA Repair; RNA Interference; RNA, Small Interfering
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175438
• Institution: National University of Singapore

10.1038/srep19552