In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics

• Main Authors: Ai X., Ho C.J.H., Aw J., Attia A.B.E., Mu J., Wang Y., Wang X., Liu X., Chen H., Gao M., Chen X., Yeow E.K.L., Liu G., Olivo M., Xing B.
• Other Authors: CHEMISTRY
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: 2 cyanobenzothiazole; benzothiazole derivative; cathepsin; cysteine; nanomaterial; peptide; photosensitizing agent; singlet oxygen; unclassified drug; upconversion nanoparticle; lanthanide; benzene; chemical reaction; electron; enzyme activity; medicine; nanoparticle; oxygen; precision; rare earth element; tumor; animal cell; animal experiment; animal model; animal tissue; Article; controlled study; covalent bond; cross linking; female; human; human cell; irradiation; mouse; nonhuman; photon; protein cleavage; theranostic nanomedicine; tumor localization; tumor microenvironment; animal; Bagg albino mouse; chemistry; HT-29 cell line; NIH 3T3 cell line; nude mouse; procedures; Animals; Female; HT29 Cells; Humans; Metals, Rare Earth; Mice; Mice, Inbred BALB C; Mice, Nude; Nanostructures; NIH 3T3 Cells; Photons; Singlet Oxygen; Theranostic Nanomedicine
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175441

10.1038/ncomms10432