Experimental model for successful liver cell therapy by lenti ttr-yapert2 transduced hepatocytes with tamoxifen control of yap subcellular location

• Main Authors: Yovchev, M, Jaber, F.L, Lu, Z, Patel, S, Locker, J, Rogler, L.E, Murray, J.W, Sudol, M, Dabeva, M.D, Zhu, L, Shafritz, D.A
• Other Authors: PHYSIOLOGY
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: hybrid protein; nuclear protein; prealbumin; tamoxifen; transcription factor; YY1AP1 protein, human; animal; animal model; biological therapy; drug effects; gene expression; gene vector; genetic transduction; genetics; Lentivirinae; liver cell; liver regeneration; metabolism; promoter region; protein transport; rat; reporter gene; transplantation; Animals; Cell- and Tissue-Based Therapy; Gene Expression; Genes, Reporter; Genetic Vectors; Hepatocytes; Lentivirus; Liver Regeneration; Models, Animal; Nuclear Proteins; Prealbumin; Promoter Regions, Genetic; Protein Transport; Rats; Recombinant Fusion Proteins; Tamoxifen; Transcription Factors; Transduction, Genetic
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175444
• Institution: National University of Singapore

10.1038/srep19275