Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission

10.18632/oncotarget.11161

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Main Authors:	Shyamsunder, P, Esner, M, Barvalia, M, Wu, Y.J, Loja, T, Boon, H.B, Lleonart, M.E, Verma, R.S, Krejci, L, Lyakhovich, A
Other Authors:	CANCER SCIENCE INSTITUTE OF SINGAPORE
Format:	Article
Published:	Impact Journals LLC 2020
Subjects:	dynamin related protein 1 guanosine triphosphatase hydroxymethylglutaryl coenzyme A reductase kinase membrane protein parkin protein PINK1 reactive oxygen metabolite small interfering RNA unclassified drug Article autolysosome autophagy controlled study disease association disorders of mitochondrial functions down regulation Fanconi anemia flow cytometry fluorescence activated cell sorting gene expression regulation gene silencing genetic transfection human human cell intracellular signaling lysosome mitochondrial biogenesis mitochondrial dynamics mitochondrial fission mitochondrial volume mitophagy molecular dynamics oxidative stress phenotype scanning electron microscopy transmission electron microscopy upregulation validation process cell line fluorescence microscopy metabolism mitochondrion pathology pathophysiology rare disease ultrastructure Autophagy Cell Line Fanconi Anemia Humans Microscopy, Electron, Transmission Microscopy, Fluorescence Mitochondria Mitochondrial Degradation Mitochondrial Dynamics Oxidative Stress Rare Diseases Reactive Oxygen Species
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/175453
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-175453
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spelling	sg-nus-scholar.10635-1754532024-04-08T14:33:25Z Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission Shyamsunder, P Esner, M Barvalia, M Wu, Y.J Loja, T Boon, H.B Lleonart, M.E Verma, R.S Krejci, L Lyakhovich, A CANCER SCIENCE INSTITUTE OF SINGAPORE ANATOMY dynamin related protein 1 guanosine triphosphatase hydroxymethylglutaryl coenzyme A reductase kinase membrane protein parkin protein PINK1 reactive oxygen metabolite small interfering RNA unclassified drug Article autolysosome autophagy controlled study disease association disorders of mitochondrial functions down regulation Fanconi anemia flow cytometry fluorescence activated cell sorting gene expression regulation gene silencing genetic transfection human human cell intracellular signaling lysosome mitochondrial biogenesis mitochondrial dynamics mitochondrial fission mitochondrial volume mitophagy molecular dynamics oxidative stress phenotype scanning electron microscopy transmission electron microscopy upregulation validation process cell line Fanconi anemia fluorescence microscopy metabolism mitochondrion pathology pathophysiology rare disease ultrastructure Autophagy Cell Line Fanconi Anemia Humans Microscopy, Electron, Transmission Microscopy, Fluorescence Mitochondria Mitochondrial Degradation Mitochondrial Dynamics Oxidative Stress Rare Diseases Reactive Oxygen Species 10.18632/oncotarget.11161 Oncotarget 7 36 58065-58074 2020-09-10T01:44:23Z 2020-09-10T01:44:23Z 2016 Article Shyamsunder, P, Esner, M, Barvalia, M, Wu, Y.J, Loja, T, Boon, H.B, Lleonart, M.E, Verma, R.S, Krejci, L, Lyakhovich, A (2016). Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission. Oncotarget 7 (36) : 58065-58074. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.11161 19492553 https://scholarbank.nus.edu.sg/handle/10635/175453 Impact Journals LLC Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	dynamin related protein 1 guanosine triphosphatase hydroxymethylglutaryl coenzyme A reductase kinase membrane protein parkin protein PINK1 reactive oxygen metabolite small interfering RNA unclassified drug Article autolysosome autophagy controlled study disease association disorders of mitochondrial functions down regulation Fanconi anemia flow cytometry fluorescence activated cell sorting gene expression regulation gene silencing genetic transfection human human cell intracellular signaling lysosome mitochondrial biogenesis mitochondrial dynamics mitochondrial fission mitochondrial volume mitophagy molecular dynamics oxidative stress phenotype scanning electron microscopy transmission electron microscopy upregulation validation process cell line Fanconi anemia fluorescence microscopy metabolism mitochondrion pathology pathophysiology rare disease ultrastructure Autophagy Cell Line Fanconi Anemia Humans Microscopy, Electron, Transmission Microscopy, Fluorescence Mitochondria Mitochondrial Degradation Mitochondrial Dynamics Oxidative Stress Rare Diseases Reactive Oxygen Species
spellingShingle	dynamin related protein 1 guanosine triphosphatase hydroxymethylglutaryl coenzyme A reductase kinase membrane protein parkin protein PINK1 reactive oxygen metabolite small interfering RNA unclassified drug Article autolysosome autophagy controlled study disease association disorders of mitochondrial functions down regulation Fanconi anemia flow cytometry fluorescence activated cell sorting gene expression regulation gene silencing genetic transfection human human cell intracellular signaling lysosome mitochondrial biogenesis mitochondrial dynamics mitochondrial fission mitochondrial volume mitophagy molecular dynamics oxidative stress phenotype scanning electron microscopy transmission electron microscopy upregulation validation process cell line Fanconi anemia fluorescence microscopy metabolism mitochondrion pathology pathophysiology rare disease ultrastructure Autophagy Cell Line Fanconi Anemia Humans Microscopy, Electron, Transmission Microscopy, Fluorescence Mitochondria Mitochondrial Degradation Mitochondrial Dynamics Oxidative Stress Rare Diseases Reactive Oxygen Species Shyamsunder, P Esner, M Barvalia, M Wu, Y.J Loja, T Boon, H.B Lleonart, M.E Verma, R.S Krejci, L Lyakhovich, A Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission
description	10.18632/oncotarget.11161
author2	CANCER SCIENCE INSTITUTE OF SINGAPORE
author_facet	CANCER SCIENCE INSTITUTE OF SINGAPORE Shyamsunder, P Esner, M Barvalia, M Wu, Y.J Loja, T Boon, H.B Lleonart, M.E Verma, R.S Krejci, L Lyakhovich, A
format	Article
author	Shyamsunder, P Esner, M Barvalia, M Wu, Y.J Loja, T Boon, H.B Lleonart, M.E Verma, R.S Krejci, L Lyakhovich, A
author_sort	Shyamsunder, P
title	Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission
title_short	Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission
title_full	Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission
title_fullStr	Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission
title_full_unstemmed	Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission
title_sort	impaired mitophagy in fanconi anemia is dependent on mitochondrial fission
publisher	Impact Journals LLC
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/175453
_version_	1800914370534834176

Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission

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