Phylodynamics of H1N1/2009 influenza reveals the transition from host adaptation to immune-driven selection

• Main Authors: Su, Y.C.F, Bahl, J, Joseph, U, Butt, K.M, Peck, H.A, Koay, E.S.C, Oon, L.L.E, Barr, I.G, Vijaykrishna, D, Smith, G.J.D
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: adaptation; antigen; disease transmission; evolutionary biology; genetic variation; immune response; influenza; natural selection; virus; 2009 H1N1 influenza; animal cell; antigenicity; Article; dynamics; genetic variability; human; investigative procedures; nonhuman; pandemic; seasonal influenza; Singapore; animal; dog; genetic selection; genetics; host pathogen interaction; immunology; Influenza A virus (H1N1); MDCK cell line; molecular evolution; molecular genetics; phylogeny; phylogeography; virus genome; Singapore [Southeast Asia]; Suidae; Adaptation, Biological; Animals; Dogs; Evolution, Molecular; Genome, Viral; Host-Pathogen Interactions; Humans; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; Molecular Sequence Data; Pandemics; Phylogeny; Phylogeography; Selection, Genetic
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175493
• Institution: National University of Singapore

10.1038/ncomms8952